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Perfluorohexane-encapsulated mesoporous silica nanocapsules as enhancement agents for highly efficient high intensity focused ultrasound (HIFU).
Xia Wang et al.
Advanced materials (Deerfield Beach, Fla.), 24(6), 785-791 (2012-01-10)
Ming-Wei Chang et al.
Langmuir : the ACS journal of surfaces and colloids, 26(7), 5115-5121 (2010-01-26)
The feasibility of producing a hollow microsphere with a single hole in its shell by coaxial electrohydrodynamic atomization (CEHDA) is demonstrated. Polymethylsilsesquioxane (PMSQ) was used as a model shell material encapsulating a core of a volatile liquid, perfluorohexane (PFH), which
Reaction of hexafluorobenzene and tetradecafluorohexane with lithium amalgam.
Kavan L and Dousek FP.
Journal of Fluorine Chemistry, 41(3), 383-391 (1988)
Synthetic Communications, 26, 1861-1861 (1996)
Liselotte M Kornmann et al.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 10(5), 264-270 (2008-06-10)
We investigated in vitro the potential of macrophages to act as targeted vehicle for ultrasound molecular imaging. Murine bone marrow-derived macrophages (BMM), incubated for 3 h with different concentrations of perfluorohexane (PFH) emulsions, were monitored by microscopy, flow cytometry, and
Koichi Kitaguchi et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 30(6), 687-690 (2014-06-13)
A fluorocarbon and hydrocarbon organic solvent mixture is known as a temperature-induced phase-separation solution. When a mixed solution of tetradecafluorohexane as a fluorocarbon organic solvent and hexane as a hydrocarbon organic solvent (e.g., 71:29 volume ratio) was delivered in a
Dirk Haufe et al.
Artificial cells, blood substitutes, and immobilization biotechnology, 39(4), 239-246 (2011-01-26)
The intraperitoneal instillation of perfluorocarbons augmented systemic oxygenation and was protective in mesenteric ischemia-reperfusion and experimental lung injury. To study biocompatibility and potential anti-inflammatory effects of intraperitoneal perfluorocarbons, we evaluated the influence of perfluorohexane and/or inflammatory stimuli on human mesothelial
Frédéric Gaboyer et al.
Research in microbiology, 165(7), 490-500 (2014-08-03)
A novel halophilic bacterium, strain RHS90(T), was isolated from marine sediments from the Gulf of Lions, in the Mediterranean Sea. Its metabolic and physiological characteristics were examined under various cultural conditions, including exposure to stressful ones (oligotrophy, high pressure and
James R Lattin et al.
Journal of pharmaceutical sciences, 104(4), 1373-1384 (2015-02-03)
Liposomes containing emulsion droplets (eLiposomes) were studied as ultrasound-responsive liposomal drug carriers. This paper presents the effects of temperature, eLiposome size, and ultrasound parameters on the ultrasonically actuated release of calcein, to test hypotheses concerning the physics of acoustic droplet
Davide R Ceratti et al.
Advanced materials (Deerfield Beach, Fla.), 27(34), 4958-4962 (2015-07-23)
A new, simple bi-phasic dip-coating method is developed. This method is considered as a great improvement of the technique for research, development and production, since expensive, rare, harmful, or time-evolving solutions can now be easily deposited on large surfaces and
Charlotta Rylander et al.
Journal of environmental monitoring : JEM, 11(11), 2002-2008 (2009-11-06)
The associations between age, body mass index (BMI), parity, place of residence (coastal or inland) and plasma concentrations of perfluorinated compounds (PFCs) were assessed in a study population from south central Vietnam. The study group consisted of 91 delivering women
Lisbeth Stigaard Kjeldsen et al.
Environmental science and pollution research international, 20(11), 8031-8044 (2013-06-15)
Perfluorinated compounds (PFCs) are a large group of chemicals used in different industrial and commercial applications. Studies have suggested the potential of some PFCs to disrupt endocrine homeostasis, increasing the risk of adverse health effects. This study aimed to elucidate
Amanda L Martin et al.
Ultrasound in medicine & biology, 38(10), 1799-1810 (2012-08-28)
Perfluorocarbon (PFC) nanodroplets (NDs) have been proposed as phase-change contrast agents for ultrasound imaging. Since the ultrasound energy required to convert PFC droplets to microbubbles is inversely related to size, the conversion of PFC NDs at clinically-relevant pressures is challenging.
James R Lattin et al.
Journal of drug targeting, 23(5), 469-479 (2015-02-13)
Vaporizing emulsion droplets may aid in endosomal rupture as a drug delivery route to the cytosol. Upon insonation, emulsion droplets formed from perfluorocarbon liquids may vaporize with sufficient expansion to disrupt liposomal or endosomal membranes. Emulsion droplets of perfluorohexane (PFC6)
Zohra Mana et al.
International journal of pharmaceutics, 338(1-2), 231-237 (2007-03-21)
Commonly, the microencapsulation of a lipophilic drug in a polymeric matrix via an ordinary oil/oil emulsification allows entrapping limited drug amounts due to its loss into the external phase. In this present paper, a new microencapsultion method describes the use
T Hölscher et al.
AJNR. American journal of neuroradiology, 28(4), 635-639 (2007-04-10)
To test a new contrast-specific sonography imaging method that offers visualization of the intracranial vasculature in a manner similar to that seen on angiography. Thirty patients (35 sonography studies total) were included in the study after they provided written informed
Sheng Song et al.
Acta biomaterialia, 24, 266-278 (2015-06-27)
In this work, superparamagnetic self-assembled microbubbles (SAMBs) consisting of "Poly(acrylic acid)-Iron oxide nanoparticles-Polyamine" sandwich-like shells and tetradecafluorohexane cores were fabricated by a template-free self-assembly approach. The SAMBs exhibit not only magnetic resonance (MR) T2 imaging functionality, but also ultrasound (US)
Xia Wang et al.
Biomaterials, 34(8), 2057-2068 (2012-12-19)
Au nanoparticles-coated, perfluorohexane-encapsulated and PEGylated mesoporous silica nanocapsule-based enhancement agents (MSNC@Au-PFH-PEG, abb. as MAPP) have been synthesized, for the ultrasound-induced cytoclasis, contrast-intensified ultrasound (US) imaging and US-guided high intensity focused ultrasound (HIFU) surgical therapy. Both the US-induced thermal effect and
Sara Persson et al.
Environment international, 59, 425-430 (2013-08-10)
This study investigates the influence of biological and environmental factors on the concentrations of perfluoroalkyl acids (PFAAs) in a top predator; the American mink. Perfluorobutane sulfonate (PFBS), perfluorohexane sulfonate (PFHxS), perfluorooctane sulfonate (PFOS) and perfluoroalkyl carboxylates (PFCAs) with C8-C13 perfluorinated
L-M L Toms et al.
Environment international, 71, 74-80 (2014-07-02)
Some perfluoroalkyl and polyfluoroalkyl substances (PFASs) have become widespread pollutants detected in human and wildlife samples worldwide. The main objective of this study was to assess temporal trends of PFAS concentrations in human blood in Australia over the last decade
Jörg U Bleyl et al.
Pulmonary pharmacology & therapeutics, 23(5), 450-455 (2010-04-07)
We investigated the effects of vaporized perfluorohexane (PFH) on pulmonary vascular tone, pulmonary vascular resistance and peak inspiratory pressure as well as lipid mediator formation in the treatment of calcium ionophore induced lung injury in a model of the isolated
Phuc Nghia Nguyen et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 12(14), 2646-2652 (2011-08-03)
The adsorption dynamics of a series of phospholipids (PLs) at the interface between an aqueous solution or dispersion of the PL and a gas phase containing the nonpolar, nonamphiphilic linear perfluorocarbon perfluorohexane (PFH) was studied by bubble profile analysis tensiometry.
Jana H Johansson et al.
Environmental pollution (Barking, Essex : 1987), 188, 102-108 (2014-03-04)
The aim of this study was to determine how dietary exposure to PFAAs has changed over the period when major production changes occurred. Archived samples (1999-2010) of eggs, milk and farmed rainbow trout were analyzed by ultra performance liquid chromatography
Michael E Kurczy et al.
Nature communications, 6, 5998-5998 (2015-01-21)
Fluorocarbons are lipophobic and non-polar molecules that exhibit remarkable biocompatibility, with applications in liquid ventilation and synthetic blood. The unique properties of these compounds have also enabled mass spectrometry imaging of tissues where the fluorocarbons act as a Teflon-like coating
Maher Abla et al.
The Journal of organic chemistry, 76(7), 2084-2093 (2011-03-10)
The advantages of using hemifluorinated surfactants as an efficient alternative to detergents for manipulating membrane proteins in aqueous solution have been demonstrated in recent reports. However, the large-scale synthesis of these surfactants is still considered as a major matter and
Yuko Kono et al.
Journal of vascular and interventional radiology : JVIR, 18(1 Pt 1), 57-65 (2007-02-14)
To determine whether contrast-enhanced ultrasound (CEUS) can aid in assessing treatment efficacy within the first 2 weeks after transarterial chemoembolization for hepatocellular carcinoma. Contrast-enhanced ultrasound was performed to detect residual tumor blood flow after 42 transarterial chemoembolization procedures in 33
Michael P Grubb et al.
Nature chemistry, 8(11), 1042-1046 (2016-10-22)
Spectroscopically observing the translational and rotational motion of solute molecules in liquid solutions is typically impeded by their interactions with the solvent, which conceal spectral detail through linewidth broadening. Here we show that unique insights into solute dynamics can be
Robert Weinmeister et al.
ACS nano, 9(10), 9718-9730 (2015-09-15)
Aqueous microdroplets with a volume of a few femtoliters are an ideal sample size for single-molecule fluorescence experiments. In particular, they enable prolonged measurements to be made on individual molecules that can diffuse freely in the surrounding medium. However, the
Journal of Heat Transfer, 118, 429-429 (1996)
Journal of the American Chemical Society, 118, 5312-5312 (1996)
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