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Brian H White et al.
Journal of the American Chemical Society, 125(48), 14901-14904 (2003-12-04)
Ring-opening/ring-closing metathesis on cyclobutene-containing substrates with angular oxygen functionality provides a stereospecific introduction of 1,5-bis-dienes required for an anion-accelerated oxy-Cope rearrangement. The reaction sequence offers generally a stereocontrolled preparation of a variety of medium ring-containing bicyclic ring systems, while rearrangement...
S Imhof et al.
Chemical communications (Cambridge, England), (17), 1692-1693 (2002-09-21)
The E-selective cross metathesis (CM) of fluorinated olefins with various functionalised alkenes in good to excellent yields is reported.
T M Trnka et al.
Accounts of chemical research, 34(1), 18-29 (2001-02-15)
In recent years, the olefin metathesis reaction has attracted widespread attention as a versatile carbon-carbon bond-forming method. Many new applications have become possible because of major advances in catalyst design. State-of-the-art ruthenium catalysts are not only highly active but also...
Structure activity relationships of 5-, 6-, and 7-methyl-substituted azepan-3-one cathepsin K inhibitors.
Yamashita DS, et al.
Journal of Medicinal Chemistry, 49(5), 1597-1612 (2006)
Schrodi, Y.; Pederson, R. L.
Aldrichimica Acta, 45-45 (2007)
Synthesis of the HCV protease inhibitor Vaniprevir (MK-7009) using ring-closing metathesis strategy.
Kong J, et al.
The Journal of Organic Chemistry, 77(8), 3820-3828 (2012)
Sequential catalysis: a metathesis/dihydroxylation sequence.
Samuel Beligny et al.
Angewandte Chemie (International ed. in English), 45(12), 1900-1903 (2006-02-14)
Kevin M Kuhn et al.
Organic letters, 12(5), 984-987 (2010-02-10)
A series of ruthenium catalysts have been screened under ring-closing metathesis (RCM) conditions to produce five-, six-, and seven-membered carbamate-protected cyclic amines. Many of these catalysts demonstrated excellent RCM activity and yields with as low as 500 ppm catalyst loadings....
Vougioukalakis, G. C.; Grubbs, R. H.
Chemical Reviews, 1746-1746 (2010)
Ian C Stewart et al.
Organic letters, 9(8), 1589-1592 (2007-03-24)
[reaction: see text] A series of ruthenium-based metathesis catalysts with N-heterocyclic carbene (NHC) ligands have been prepared in which the N-aryl groups have been changed from mesityl to mono-ortho-substituted phenyl (e.g., tolyl). These new catalysts offer an exceptional increase in...
Schuster, M.; Blechert, S.
Angewandte Chemie (International Edition in English), 2036-2036 (1997)
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