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Feng-Jen Tsai et al.
Journal of photochemistry and photobiology. B, Biology, 112, 7-15 (2012-04-28)
We present an in vivo test platform to evaluate the antioxidative capability of seven frequently used dermocosmetic antioxidants on the human stratum corneum (SC). It has been reported that the protein carbonylation could be used as a biomarker for oxidative...
Mayura Wittayasuporn et al.
Journal of microencapsulation, 27(3), 218-225 (2009-07-02)
A chitosan derivative, methyl ether-terminated poly(ethylene oxide)-4-methoxycinnamolyphthaloylchitosan (PCPLC) was prepared, characterized and self-assembled into nanoparticles. Encapsulation of ascorbyl palmitate (AP) into PCPLC gave 6890.98 nm particles with encapsulation efficiency of 84% at 56% drug loading. The encapsulated AP showed significant...
Gopa Mitra et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 149(4), 341-350 (2008-03-11)
The effect of supplementation of ascorbic acid through enriched zooplankton [10%, 20% and 30% ascorbyl palmitate (AP) inclusion in diet of zooplankton] on different digestive enzyme activities during ontogeny of Labeo rohita larvae was studied from 4 day to 15...
Lipid-soluble vitamin C palmitate and protection of human high-density lipoprotein from hypochlorite-mediated oxidation.
DeMarquis O Loyd et al.
International journal of cardiology, 152(2), 256-257 (2011-08-30)
Kyung Mi Lee et al.
Mutation research, 660(1-2), 51-56 (2008-11-26)
Although the health benefits of dietary antioxidants have been extensively studied, their potential negative effects remain unclear. L-Ascorbic acid 6-palmitate (AAP), a synthetic derivative of ascorbic acid (AA), is widely used as an antioxidant and preservative in foods, vitamins, drugs...
Ascorbyl palmitate and its synergism to tocopherols.
Karl-Heinz Wagner et al.
Forum of nutrition, 56, 347-348 (2005-04-06)
Dilyana Paneva et al.
International journal of pharmaceutics, 416(1), 346-355 (2011-07-06)
The one-step incorporation of ascorbyl palmitate (AP), a widely used derivative of vitamin C, into nanofibrous mats of poly(ɛ-caprolactone) (PCL) by electrospinning was demonstrated. The incorporation of AP was attested by IR spectroscopy; the AP content was determined by thermogravimetric...
Sandra Barata-Antunes et al.
International journal of molecular sciences, 21(10) (2020-05-20)
Parkinson's disease (PD) is the second most common age-related neurodegenerative disorder. The neurodegeneration leading to incapacitating motor abnormalities mainly occurs in the nigrostriatal pathway due to the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Several animal...
Michelle Olsher et al.
Analytical biochemistry, 382(1), 1-8 (2008-08-13)
We have developed a fluorescence method to examine how membrane sterol lateral organization affects the potency of antioxidants, and used this information to evaluate possible adverse effects of lipid-soluble antioxidants seen in recent clinical studies. In the presence of an...
Lingyan Kong et al.
Carbohydrate polymers, 111, 256-263 (2014-07-20)
In the present study, we introduce a simple method to prepare inclusion complexes by "inserting" guest molecules into preformed "empty" V-type amylose helices. Ascorbyl palmitate (AscP) was used as a model guest material to investigate the effect of solvent environment...
PA and fish oil.
A Carmichael
British dental journal, 212(8), 356-357 (2012-04-28)
Charlotte Jacobsen
Annals of the New York Academy of Sciences, 1190, 141-150 (2010-04-15)
Enrichment of foods with marine omega-3 polyunsaturated fatty acids (PUFA) poses a multidisciplinary challenge to food industry and academia. Although our knowledge about possible health effects of omega-3 PUFA has increased tremendously during the last 30 years, there is still...
Luciano Benedini et al.
Colloids and surfaces. B, Biointerfaces, 89, 265-270 (2011-10-15)
Ascorbyl palmitate (Asc16) in polyethyleneglycol 400 (PEG 400)-water mixtures at weight fractions (w/w) between 0.05 and 1.0 were studied by differential scanning calorimetry (DSC) and polarizing microscopy (PM) at different temperatures. The employed PEG 400-water proportions were: 0-25-50% and 75%...
Li Xiao et al.
Molecular and cellular biochemistry, 394(1-2), 247-259 (2014-06-06)
The aim of this study was to investigate protective effects of the lipophilic vitamin C derivative, 6-o-palmitoylascorbate (PlmtVC), against X-ray radiation-induced damages including cell death, DNA double-strand breaks (DSBs), lipid peroxidation, and protein carbonylation in human lymphocytes HEV0082, and the...
Bárbara Mendes-Pinheiro et al.
Stem cells translational medicine, 7(11), 829-838 (2018-09-22)
Parkinson's disease (PD) is a progressive neurodegenerative movement disorder that results from the death of dopamine (DA) neurons. Over recent years, differentiated or undifferentiated neural stem cells (NSCs) transplantation has been widely used as a means of cell replacement therapy....
Luciano Benedini et al.
Langmuir : the ACS journal of surfaces and colloids, 27(17), 10914-10919 (2011-07-20)
Ascorbyl palmitate (ASC(16)) is a molecule of potential pharmacological interest due to its antioxidant properties and amphiphilic nature. The surface behavior of ASC(16) was studied using Langmuir monolayers and Brewster angle microscopy. This molecule formed stable monolayers at room temperature...
M M Almeida et al.
International journal of cosmetic science, 31(6), 445-450 (2009-05-27)
A rapid HPLC method was developed for the assay of tocopheryl acetate and ascorbyl tetraisopalmitate in cosmetic formulations. The validated method was applied for quantitative determination of these vitamins in simulated emulsion formulation. Samples were analysed directly on a RP-18...
Martin Spickenreither et al.
Bioorganic & medicinal chemistry letters, 16(20), 5313-5316 (2006-08-16)
Previously, we identified ascorbic acid 6-O-hexadecanoate as an up to 1500 times more potent inhibitor of bacterial and bovine hyaluronidases than the parent compound, vitamin C, and determined a crystal structure of hyaluronidase from Streptococcus pneumoniae in complex with the...
Mostafa Nakach et al.
International journal of pharmaceutics, 476(1-2), 277-288 (2014-10-04)
This paper describes a systematic approach to select optimum stabilizer for the preparation of nano-crystalline suspensions of an active pharmaceutical ingredient (API). The stabilizer can be either a dispersant or a combination of dispersant and wetting agent. The proposed screening...
Yali Yuan et al.
Analytica chimica acta, 701(2), 169-173 (2011-08-02)
Vitamin C derivatives (VCDs) have been widely used as the alternative and stable sources of vitamin C, and accordingly exhibit many new applications, such as anti-tumor and central nervous system drug delivery. In this study, their Ru(bpy)(3)(2+) electrochemiluminescence (ECL) properties...
Mi Kyung Kim et al.
Colloids and surfaces. B, Biointerfaces, 103, 391-394 (2012-12-19)
The aim of this study was to produce ascorbyl palmitate (AP)-loaded nanoparticles in order to inhibit polyphenol oxidase (PPO) in bananas. AP-loaded chitosan nanoparticles were prepared using acetic acid and citric acid (denoted as CS/AA and CS/CA nanoparticles, respectively). As...
Atikorn Panya et al.
Journal of agricultural and food chemistry, 63(34), 7546-7555 (2015-08-15)
Development of an antioxidant assay explaining antioxidant behaviors in complex food systems has been a challenging topic for food scientists. This research aimed to investigate antioxidant capacities and interactions of selected synthetic antioxidants and commercial natural antioxidant extracts using the...
Chen-Yuan Hsiao et al.
Frontiers in endocrinology, 11, 613-613 (2020-10-06)
Calcitonin is a small peptide hormone secreted from the parafollicular cells of the thyroid gland in response to an increase in serum calcium. The inhibition of osteoclastic resorption is the main mechanism by which calcitonin quickly decreases circulating calcium levels....
Lindomar A Lerin et al.
Ultrasonics sonochemistry, 18(5), 988-996 (2011-01-29)
This work is focused on the optimization of reaction parameters for the synthesis of ascorbyl palmitate catalyzed by Candida antarctica lipase in different organic solvents under ultrasound irradiation. The sequential strategy of experimental design proved to be useful in determining...
J H Han et al.
Journal of food science, 73(8), E349-E355 (2008-11-21)
Physical properties of whey protein isolate (WPI) coating solution incorporating ascorbic palmitate (AP) and alpha-tocopherol (tocopherol) were characterized, and the antioxidant activity of dried WPI coatings against lipid oxidation in roasted peanuts were investigated. The AP and tocopherol were mixed...
Stephan Braun et al.
European journal of medicinal chemistry, 46(9), 4419-4429 (2011-08-02)
Bacterial hyaluronan lyases (Hyal) degrade hyaluronan, an important component of the extracellular matrix, and are involved in microbial spread. Hyal inhibitors may serve as tools to study the role of the enzyme, its substrates and products in the course of...
Rangrong Yoksan et al.
Colloids and surfaces. B, Biointerfaces, 76(1), 292-297 (2009-12-17)
The encapsulation of ascorbyl palmitate (AP) in chitosan particles was carried out by droplet formation via an oil-in-water emulsion, followed by droplet solidification via ionic gelation using sodium triphosphate pentabasic (TPP) as a cross-linking agent. The success of AP encapsulation...
Rupa R Sawant et al.
Pharmaceutical research, 29(2), 375-383 (2011-08-17)
To evaluate and compare anticancer therapeutic effect of palmitoyl ascorbate liposomes (PAL) and free ascorbic acid (AA). Liposomes incorporating palmitoyl ascorbate (PA) were prepared and evaluated for PA content by HPLC. To elucidate mechanism of action of cell death in...
Mirjam Gosenca et al.
AAPS PharmSciTech, 11(3), 1485-1492 (2010-09-17)
The aim of this work was to test innovative approach for enhancing ascorbyl palmitate stability in microemulsions for topical application by addition of newly synthesized co-antioxidant 4-(tridecyloxy)benzaldehyde oxime (TDBO) and to investigate its antioxidant activity and finally to evaluate cytotoxicity...
Raju Jukanti et al.
Journal of microencapsulation, 28(2), 142-149 (2011-01-27)
The aim of this study is to develop ascorbyl palmitate (ASP) loaded doxorubicin (DOX) pegylated liposomes and to evaluate their targeting potential to tumor. We have prepared conventional (DL), pegylated DOX liposomes with (SDL) and without ascorbyl palmitate (SDL-A). The...