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Classical pharma manufacturing
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Improving API Solubility
This article describes the solubility challenge presented by many small molecule APIs and strategies to overcome these issues during the formulation process.
Comparison of Preservatives Used in Various Therapeutic Applications
Find key considerations for the selection and use of benzalkonium chloride, benzyl alcohol, benzaldehyde, parabens, benzoic acid, and sodium benzoate as preservatives.
Strategies for the Development of Safe and Effective Pediatric Formulations
Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric
Overcoming Excipient Risks and Challenges for Parenteral Formulations
This overview describes the challenges when developing parenteral formulations and strategies to overcome them and reduce the risk of production.
Criteria for Selecting Preservatives Used in Liquid Formulation
Find key considerations for the selection and use of preservatives in a range of different therapeutic applications including topical, oral, transmucosal, inhalation, and otic, as well as injectables.
Liquid Formulation Solubility Enhancement
Discover strategies to enhance solubility in injectable formulations using excipients, including cyclodextrins, meglumine, and polyethylene glycols.
Improving API Solubility Using Spray Drying with Polyvinyl Alcohol
Discover how spray drying with polyvinyl alcohol enhances solubility for small and large molecule drugs and unlocks the potential of poorly soluble APIs.
Improving API Solubility with Mesoporous Silica
Discover how mesoporous silica enhances API solubility, unlocking the full potential of promising drugs with improved bioavailability.