显示 1-30 共 35 条结果 关于 "GF04779894"
[Agents for the treatment of leishmaniasis. Antimony, and more].
Jasmin Ryczak et al.
Pharmazie in unserer Zeit, 38(6), 538-544 (2009-10-29)
A Léonard et al.
Mutation research, 366(1), 1-8 (1996-10-01)
The paper reviews the information available concerning the mutagenic, teratogenic and carcinogenic effects of antimony. A claim that antimony compounds could have mutagenic properties is based on insufficient and not particularly relevant data. Additional experiments, particularly with organic antimony compounds...
F Welle et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 28(1), 115-126 (2010-12-25)
Plastics bottles made from polyethylene terephthalate (PET) are increasingly used for soft drinks, mineral water, juices and beer. In this study a literature review is presented concerning antimony levels found both in PET materials as well as in foods and...
Nurit Atar et al.
ACS applied materials & interfaces, 6(22), 20400-20407 (2014-11-05)
Chemical vapor deposition (CVD)-grown entangled carbon nanotube (CNT) sheets are characterized by high electrical conductivity and durability to bending and folding. However, since freestanding CNT sheets are mechanically weak, they cannot be used as stand-alone flexible films. In this work...
Yong Chen et al.
Chemosphere, 113, 48-55 (2014-07-30)
The interlayer of Sb-doped SnO2 (SnO2-Sb) and TiO2 nanotubes (TiO2-NTs) on Ti has been introduced into the PbO2 electrode system with the aim to reveal the mechanism of enhanced electrochemical performance of TiO2-NTs/SnO2-Sb/PbO2 electrode. In contrast with the traditional Ti/SnO2-Sb/PbO2...
Ronald Bentley et al.
Microbiology and molecular biology reviews : MMBR, 66(2), 250-271 (2002-06-01)
A significant 19th century public health problem was that the inhabitants of many houses containing wallpaper decorated with green arsenical pigments experienced illness and death. The problem was caused by certain fungi that grew in the presence of inorganic arsenic...
Ashutosh et al.
Journal of medical microbiology, 56(Pt 2), 143-153 (2007-01-25)
Leishmaniasis causes significant morbidity and mortality worldwide. The disease is endemic in developing countries of tropical regions, and in recent years economic globalization and increased travel have extended its reach to people in developed countries. In the absence of effective...
Y Xue et al.
Journal of dental research, 94(5), 674-681 (2015-03-04)
Cathepsin K (CTSK) is an important protease responsible for degrading type I collagen, osteopontin, and other bone matrix proteins. The mutations in the CTSK gene can cause pycnodysostosis (OMIM 265800), a rare autosomal recessive bone dysplasia. Patients with pycnodysostosis have...
Pankaj Sharma et al.
Acta pharmacologica Sinica, 29(8), 881-890 (2008-07-31)
Antimony, a natural element that has been used as a drug for over more than 100 years, has remarkable therapeutic efficacy in patients with acute promyelocytic leukemia. This review focuses on recent advances in developing antimony anticancer agents with an...
Stephanie R Gerla et al.
Journal of water and health, 13(3), 819-826 (2015-09-01)
Water storage is one of the most important components of emergency preparedness. Potable water is needed for ensuring the survival and well-being of disaster victims. Consumers may store water in previously used beverage or other food-grade containers for emergency use;...
Martin Wiener et al.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 67(8), 1038-1044 (2014-06-15)
Recommended selective neck dissections for primary cutaneous tumours on the head and neck are based largely on clinical recurrence data acquired prior to the era of lymphatic mapping and sentinel lymph node (SLN) biopsy. This study aimed to examine lymphatic...
Patricia Smichowski
Talanta, 75(1), 2-14 (2008-03-29)
This review summarizes and discusses the research carried out on the determination of antimony and its predominant chemical species in atmospheric aerosols. Environmental matrices such as airborne particulate matter, fly ash and volcanic ash present a number of complex analytical...
M J Nash et al.
Journal of environmental monitoring : JEM, 2(2), 97-109 (2001-03-17)
Methodologies for the environmental analysis of total antimony and aqueous chemical speciation are critically reviewed, including preparation techniques for aqueous and solid matrices and the determination of solid state partitioning and recommendations are given for future research directions. Concentrations of...
Eric Allcorn et al.
Physical chemistry chemical physics : PCCP, 17(43), 28837-28843 (2015-10-10)
The diffusion coefficient of lithium is an important parameter in determining the rate capability of an electrode and its ability to deliver high power output. Galvanostatic intermittent titration technique (GITT) is a quick electrochemical method to determine diffusion coefficients in...
P Kaur et al.
Plasmid, 27(1), 29-40 (1992-01-01)
Resistance determinants to the toxic oxyanionic salts of arsenic and antimony are found on plasmids of both gram-negative and gram-positive organisms. In most cases these provide resistance to both the oxyanions of +III oxidation state, antimonite and arsenite, and the...
William Shotyk et al.
Metal ions in biological systems, 44, 171-203 (2005-06-24)
Antimony is a potentially toxic trace element with no known biological function. Antimony is commonly enriched in coals, and fossil fuel combustion appears to be the largest single source of anthropogenic Sb to the global atmosphere. Abundant in sulfide minerals...
T Gebel
Chemico-biological interactions, 107(3), 131-144 (1998-02-04)
A chemico-toxicological similarity between arsenic and antimony exists and their toxicology is often seen. Indeed, both elements possess several common properties, e.g. they are clastogenic but not mutagenic in the trivalent state and they have a carcinogenic potential: trivalent arsenicals...
Edward R T Tiekink
Critical reviews in oncology/hematology, 42(3), 217-224 (2002-06-07)
The main group elements antimony and bismuth are used clinically, primarily for the treatment of Leishmaniasis (antimony) and ulcers (bismuth). Despite their medicinal efficacy, the exploration of the anti-cancer potential of antimony and bismuth compounds is not as well developed...
Khatima Aït-Oudhia et al.
Parasitology research, 109(5), 1225-1232 (2011-07-30)
Leishmania is the causative agent of various forms of leishmaniasis, a significant cause of morbidity and mortality. The clinical manifestations of the disease range from self-healing cutaneous and mucocutaneous skin ulcers to a fatal visceral form named visceral leishmaniasis or...
Shouhei Ogawa et al.
Environmental technology, 36(20), 2647-2656 (2015-04-22)
This study investigated whether a combined application of hydroxyapatite and ferrihydrite could immobilize lead and antimony in shooting range soil in which the level of lead contamination is markedly higher than that of antimony. In addition, we evaluated the stability...
Graça Brito et al.
The American journal of tropical medicine and hygiene, 90(4), 617-620 (2014-02-26)
Pentoxifylline is a tumor necrosis factor-α (TNF-α) inhibitor that also attenuates the immune response and decreases tissue inflammation. The association of pentoxifylline with antimony improves the cure rate of mucosal and cutaneous leishmaniasis. In this randomized and double blind pilot...
Rajmund Michalski et al.
TheScientificWorldJournal, 2012, 902464-902464 (2012-06-02)
Due to the fact that metals and metalloids have a strong impact on the environment, the methods of their determination and speciation have received special attention in recent years. Arsenic, antimony, and thallium are important examples of such toxic elements....
Mohammad Eftekhari et al.
Environmental monitoring and assessment, 187(1), 4129-4129 (2014-11-19)
Vortex-assisted surfactant-enhanced emulsification microextraction based on solidification of floating organic drop (VASEME-SFO) was used for preconcentration and speciation of antimony (ΙΙΙ, V) followed by electrothermal atomic absorption spectrometry (ETAAS). In this procedure, Triton X-114 was used as emulsifier and 1-undecanol...
Antimony trioxide and antimony trisulfide.
IARC monographs on the evaluation of carcinogenic risks to humans, 47, 291-305 (1989-01-01)
Shyam Sundar et al.
International journal of environmental research and public health, 7(12), 4267-4277 (2011-02-15)
Antimony toxicity occurs either due to occupational exposure or during therapy. Occupational exposure may cause respiratory irritation, pneumoconiosis, antimony spots on the skin and gastrointestinal symptoms. In addition antimony trioxide is possibly carcinogenic to humans. Improvements in working conditions have...
Ricardo Khouri et al.
The Journal of infectious diseases, 210(2), 306-310 (2014-02-11)
We show that increased plasma superoxide dismutase 1 (SOD1) levels are statistically significant predictors of the failure of pentavalent antimony treatment for cutaneous leishmaniasis caused by Leishmania braziliensis. In Leishmania amazonensis-infected patients, host SOD1 levels can be used to discriminate...
Rita Mukhopadhyay et al.
Biochimica et biophysica acta, 1840(5), 1583-1591 (2013-12-03)
Aquaporins (AQPs), members of a superfamily of transmembrane channel proteins, are ubiquitous in all domains of life. They fall into a number of branches that can be functionally categorized into two major sub-groups: i) orthodox aquaporins, which are water-specific channels...
Martin J J Ronis et al.
Experimental biology and medicine (Maywood, N.J.), 240(1), 58-66 (2014-09-03)
Differences in trace element composition and bioavailability between breast milk and infant formulas may affect metal homeostasis in neonates. However, there is a paucity of controlled studies in this area. Here, piglets were fed soy infant formula (soy), cow's milk...
Maya Berg et al.
Antimicrobial agents and chemotherapy, 59(4), 2242-2255 (2015-02-04)
Together with vector control, chemotherapy is an essential tool for the control of visceral leishmaniasis (VL), but its efficacy is jeopardized by growing resistance and treatment failure against first-line drugs. To delay the emergence of resistance, the use of drug...
Marlies De Boeck et al.
Mutation research, 533(1-2), 135-152 (2003-12-04)
The purpose of this review is to summarise the data concerning genotoxicity and carcinogenicity of Co and Sb. Both metals have multiple industrial and/or therapeutical applications, depending on the considered species. Cobalt is used for the production of alloys and...

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