显示 1-30 共 127 条结果 关于 "gf10346644"
Non-intravenous approaches to iron therapy in chronic kidney disease: will it improve the benefit-to-risk ratio?
Anatole Besarab
Nephrology news & issues, 28(2), 12-12 (2014-03-22)
Crystal D Karakochuk et al.
The Journal of nutrition, 145(1), 134-142 (2014-12-21)
Anemia is common in Cambodian women. Potential causes include micronutrient deficiencies, genetic hemoglobin disorders, inflammation, and disease. We aimed to investigate factors associated with anemia (low hemoglobin concentration) in rural Cambodian women (18-45 y) and to investigate the relations between...
Vivek Kumar Srivastava et al.
The Biochemical journal, 463(1), 103-114 (2014-07-06)
Iron is an essential nutrient for all living organisms and human pathogens employ a battery of factors to scavenge iron from the high-affinity iron-binding host proteins. In the present study, we have elucidated, via a candidate gene approach, major iron...
Lucie Y Guo et al.
Experimental eye research, 129, 31-37 (2014-12-03)
Age-related macular degeneration (AMD) is the most common cause of blindness among older adults in developed countries, and retinal iron accumulation may exacerbate the disease. Iron can upregulate the production of amyloid precursor protein (APP). Since amyloid-β (Aβ), a byproduct...
Céline Termote et al.
Food and nutrition bulletin, 35(4), 458-479 (2015-02-03)
Wild foods and their actual and potential contributions to nutrition security have rarely been studied or considered in nutrition and conservation programs. To study the role of wild food biodiversity in achieving a cost reduction of a nutritionally adequate diet...
Shuichi Sekine et al.
Toxicology and applied pharmacology, 282(3), 237-243 (2014-12-30)
Patients with long-lasting hepatitis C virus (HCV) infection are at major risk of hepatocellular carcinoma (HCC). Iron accumulation in the livers of these patients is thought to exacerbate conditions of oxidative stress. Transgenic mice that express the HCV core protein...
Oliver M Theusinger
Praxis, 103(21), 1257-1262 (2014-10-12)
Blood transfusions are in general considered as lifesaving. Current data and evidence show, that blood transfusions are associated with increased morbidity and mortality, and this apparently dose-dependent. Basic research and results from randomized controlled trials show a causal relationship between...
Catherine F M Bowden et al.
Biochemistry, 53(14), 2286-2294 (2014-03-22)
The Isd (iron-regulated surface determinant) system is a multiprotein transporter that allows bacterium Staphylococcus aureus to take up iron from hemoglobin (Hb) during human infection. In this system, IsdB is a cell wall-anchored surface protein that contains two near iron...
Ewelina Łukaszyk et al.
Przeglad lekarski, 71(2), 95-97 (2014-07-16)
Subclinical inflammation is one of the key mechanisms responsible for the development and progression of chronic kidney disease. It may stem from uremia, ongoing inflammation in kidney as well as latent bacterial and viral infections. Inflammation also plays a significant...
Sandra Isabel Escobar-Megchún et al.
Journal of water and health, 12(4), 722-726 (2014-12-05)
This study relates to a method for evaluating the degradation efficiency of Ascaris lumbricoides eggs through a Fenton reaction, using hydrogen peroxide (H2O2) at 100, 250, and 500 mg/L, ferrous sulfate (FeSO4) at 458 mg/L Fe(2+) and pH values of...
The role of intravenous iron for the treatment of restless legs syndrome.
Michael Auerbach
American journal of hematology, 89(10), 1016-1016 (2014-08-05)
Koichiro Uto et al.
Journal of nanoscience and nanotechnology, 14(4), 3193-3201 (2014-04-17)
(Apo)ferritins are cage-shaped proteins which have recently received a great deal of attention because the inner cavity of the protein shell can be used as a size-restricted reaction field for the synthesis of nanomaterials. The biomineralization behavior and inorganic nanoparticle...
Jun-Won Jang et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 59(12), 2503-2507 (2009-06-23)
Zero valent iron has been successfully used for the degradation of a wide range of contaminants. However, this reaction of using ZVI particle produces a large quantity of iron sludge. To solve the problem, we report the synthesis of self-organized...
Julia Steuber et al.
Nature, 516(7529), 62-67 (2014-12-05)
NADH oxidation in the respiratory chain is coupled to ion translocation across the membrane to build up an electrochemical gradient. The sodium-translocating NADH:quinone oxidoreductase (Na(+)-NQR), a membrane protein complex widespread among pathogenic bacteria, consists of six subunits, NqrA, B, C...
Yukio Miyamoto et al.
AJR. American journal of roentgenology, 202(4), W400-W407 (2014-03-26)
The objective of our study was to compare the efficacy of contrast-enhanced ultrasound (CEUS) using the ultrasound contrast agent Sonazoid (perflubutane) with unenhanced ultrasound and supplementary contrast-enhanced MRI in the differential diagnosis (benign vs malignant) of focal breast lesions. The...
Mary K Sherwood et al.
Chemosphere, 113, 56-61 (2014-07-30)
Modified Fenton (MF) chemistry was tested in the laboratory to treat three diesel fuel-contaminated soils from the Canadian arctic rich in soil organic matter (SOM) and Fe oxides. Reactors were dosed with hydrogen peroxide (HP), and treatment was compared in...
Angelo Belotti et al.
Leukemia research, 39(1), 88-91 (2014-12-02)
We analyzed appearance of non transferrin bound iron (NTBI) in 30 transplant eligible patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) during conventional chemotherapy treatment program and evaluated possible relationship with transfusional body iron intake, iron parameters...
Florence Lima et al.
Environmental and molecular mutagenesis, 55(3), 266-277 (2014-04-12)
DNA methylation is an epigenetic mechanism that drives phenotype and that can be altered by environmental exposures including radiation. The majority of human radiation exposures occur in a relatively low dose range; however, the biological response to low dose radiation...
Roberta J Ward et al.
The Lancet. Neurology, 13(10), 1045-1060 (2014-09-19)
In the CNS, iron in several proteins is involved in many important processes such as oxygen transportation, oxidative phosphorylation, myelin production, and the synthesis and metabolism of neurotransmitters. Abnormal iron homoeostasis can induce cellular damage through hydroxyl radical production, which...
David Z Mokry et al.
Biochimica et biophysica acta, 1840(10), 3058-3066 (2014-06-28)
For many pathogenic microorganisms, iron acquisition represents a significant stress during the colonization of a mammalian host. Heme is the single most abundant source of soluble iron in this environment. While the importance of iron assimilation for nearly all organisms...
Maria Wilhelm et al.
Clinical nephrology, 81(4), 251-258 (2014-03-25)
Hyperphosphatemia in advanced chronic kidney disease (CKD) necessitates the use of phosphate binders. This in vitro study assessed phosphate binding and Fe release properties of the novel iron-based phosphate binder PA21. Phosphate adsorption and Fe release were assessed under conditions...
[Cutting-edge of medicine; iron metabolism--recent findings].
Hideo Harigae
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 102(10), 2699-2704 (2014-01-10)
Evelyn Yamal-Turbay et al.
Environmental technology, 35(13-16), 1695-1701 (2014-06-25)
Despite being acknowledged as an emerging contaminant, sulphamethazine (SMT) degradation has received scarce attention in the advanced oxidation processes field. Thus, this work addresses the degradation of SMT in water solutions (12 L of 25mgL-1 samples) by means of a...
Nanda Kumar N Shanmugam et al.
Journal of immunology (Baltimore, Md. : 1950), 193(3), 1398-1407 (2014-06-29)
States of chronic inflammation such as inflammatory bowel disease are often associated with dysregulated iron metabolism and the consequent development of an anemia that is caused by maldistribution of iron. Abnormally elevated expression of the hormone hepcidin, the central regulator...
Courtni E Allen et al.
Journal of bacteriology, 197(3), 553-562 (2014-11-19)
The use of hemin iron by Corynebacterium diphtheriae requires the DtxR- and iron-regulated ABC hemin transporter HmuTUV and the secreted Hb-binding protein HtaA. We recently described two surface anchored proteins, ChtA and ChtC, which also bind hemin and Hb. ChtA...
Mohiee El-Deen El-Aziz Awad et al.
Journal of the Egyptian Society of Parasitology, 44(3), 695-708 (2015-02-04)
This study assessed the diagnostic approaches of Helicobacter pylori (IP)-associated iron deficiency (ID) and anemia (IDA) in children with dyspeptic symptoms and evaluated the effect of simultaneous anti-H. pylori (anti-HIP) therapy and oral iron in comparison with each of anti?...
Oriana Marques et al.
Cancer letters, 347(1), 1-14 (2014-02-04)
Iron is an essential element and a critical component of molecules involved in energy production, cell cycle and intermediate metabolism. However, the same characteristic chemistry that makes it so biologically versatile may lead to iron-associated toxicity as a consequence of...
Wentao Zhang et al.
Biochemical and biophysical research communications, 455(3-4), 312-317 (2014-12-03)
Serine/arginine-rich (SR) proteins are important splicing factors. However, the biological functions of plant SR proteins remain unclear especially in abiotic stresses. Cadmium (Cd) is a non-essential element that negatively affects plant growth and development. In this study, we provided clear...
Biochemistry. Fishing for peroxidase protons.
John T Groves et al.
Science (New York, N.Y.), 345(6193), 142-143 (2014-07-12)
Yingxun Liu et al.
Journal of biomedical nanotechnology, 10(8), 1574-1587 (2014-07-16)
To evaluate the effects of iron oxide nanoparticles on genes from different cell lines in this study, mouse macrophage RAW264.7 and hepatocyte Hepa1-6 cell lines were treated with DMSA-coated Fe3O4 nanoparticles. Two doses were used, 50 microg/mL and 100 microg/mL...

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