显示 1-30 共 207 条结果 关于 "GF13286369"
Marcus C de Jong et al.
Survey of ophthalmology, 60(4), 346-355 (2015-04-22)
We demonstrate the value of high-resolution magnetic resonance imaging (MRI) in diagnosing, staging, and follow-up of retinoblastoma during eye-saving treatment. We have included informative retinoblastoma cases scanned on a 3T MRI system from a retrospective retinoblastoma cohort from 2009 through...
John Stirrat et al.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 17, 66-66 (2015-08-08)
Myocardial fibrosis imaging using late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) has been validated as a quantitative predictive marker for response to medical, surgical, and device therapy. To date, all such studies have examined conventional, non-phase corrected magnitude images.  However, contemporary...
Christoph Niessen et al.
Journal of vascular and interventional radiology : JVIR, 26(5), 694-702 (2015-03-31)
To evaluate the risk factors associated with short-term local recurrence of malignant liver lesions after irreversible electroporation (IRE). Thirty-nine consecutive patients (79 malignant liver lesions) were treated with IRE, of whom 14 were excluded from the analysis (including 12 without...
Ilya Y Shadrin et al.
Scientific reports, 5, 12043-12043 (2015-07-15)
Cardiac cell therapies involving bone marrow-derived human mesenchymal stem cells (hMSCs) have shown promising results, although their mechanisms of action are still poorly understood. Here, we investigated direct interactions between hMSCs and cardiomyocytes in vitro. Using a genetic Ca(2+) indicator...
Masashi Shimohira et al.
Journal of vascular and interventional radiology : JVIR, 26(6), 856-864 (2015-04-09)
To assess reperfusion rates after coil embolization for pulmonary arteriovenous malformations (PAVMs) using time-resolved magnetic resonance (MR) angiography or pulmonary angiography. Patients with PAVMs who underwent embolization and met the following inclusion criteria were included: (a) embolization was performed using...
Qian Wang et al.
Clinical science (London, England : 1979), 127(2), 91-100 (2014-01-22)
GdCl3 (gadolinium chloride) has been shown to reduce blood glucose; however, the underlying mechanism remains unclear. Liver gluconeogenesis is an important pathway involved in the maintenance of glucose homoeostasis. The aim of the present study was to investigate the role...
Hongyu Chen et al.
Molecular pharmaceutics, 12(6), 1885-1892 (2015-04-15)
Monitoring of drugs in vivo has been recognized as an urgent need for successful chemotherapy treatment. However, to find an appropriate tool for this purpose has been proved as a great challenge. Here, we report a PLA-PEG coated hollow X-ray...
Zhuxian Zhou et al.
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology, 5(1), 1-18 (2012-10-11)
Magnetic resonance imaging (MRI) is a clinical imaging modality effective for anatomical and functional imaging of diseased soft tissues, including solid tumors. MRI contrast agents (CA) have been routinely used for detecting tumor at an early stage. Gadolinium-based CA are...
Tadanori Mammoto et al.
Developmental dynamics : an official publication of the American Association of Anatomists, 244(6), 713-723 (2015-02-27)
Mechanical compression of cells during mesenchymal condensation triggers cells to undergo odontogenic differentiation during tooth organ formation in the embryo. However, the mechanism by which cell compaction is stabilized over time to ensure correct organ-specific cell fate switching remains unknown....
Antonella Meloni et al.
International journal of cardiology, 177(3), 1012-1019 (2014-12-03)
The multislice multiecho T2* cardiovascular magnetic resonance (CMR) technique allows to detect different patterns of myocardial iron overload (MIO). The aim of this cross-sectional study was to verify the association between cardiac complications (heart failure and arrhythmias), biventricular dysfunction and...
C Lepoutre-Lussey et al.
European journal of nuclear medicine and molecular imaging, 42(6), 868-876 (2015-02-14)
Specific recommendations on screening modalities for paraganglioma (PGL) and phaeochromocytoma (PCC) in asymptomatic SDHx mutation carriers (relatives) are still lacking. We evaluated the added value of (18)F-FDG PET/CT in comparison with morphological imaging at initial diagnosis and 1 year of...
T Dragovich et al.
Cancer chemotherapy and pharmacology, 74(2), 379-387 (2014-06-19)
Vatalanib (PTK 787/ZK22584) is an oral poly-tyrosine kinase inhibitor with strong affinity for platelet-derived growth factor and vascular endothelial growth factor (VEGF) receptors. We conducted an open-label, phase II multicenter therapeutic trial investigating the efficacy and tolerability of vatalanib in...
Loïc Bière et al.
The American journal of cardiology, 116(4), 497-503 (2015-06-14)
The aim of the study was to identify the determinants of pericardial effusion (PE) after a first myocardial infarction (MI). Cardiac magnetic resonance enables early analysis of multiple post-MI parameters; 193 patients with a first ST-elevation MI admitted to the...
Dulce Neutel et al.
The journal of spinal cord medicine, 37(4), 429-431 (2014-03-14)
Differential diagnosis of acute/subacute intrinsic spinal cord lesions can be challenging. In addition, intramedullary neoplasms typically show gadolinium enhancement, mass effect, and cord expansion. We report a patient with spinal cord and brain stem lesions resembling multifocal myelitis. Magnetic resonance...
S van Grinsven et al.
Clinical radiology, 69(11), 1157-1164 (2014-09-15)
To prospectively evaluate the influence of observer experience, consensus assessment, and abduction and external rotation (ABER) view on the diagnostic performance of magnetic resonance arthrography (MRA) in patients with traumatic anterior-shoulder instability (TASI). Fifty-eight MRA examinations (of which 51 had...
Yoo Jin Hong et al.
The international journal of cardiovascular imaging, 31 Suppl 1, 115-122 (2015-01-31)
To evaluate whether the extracellular volume fraction (ECV) measured using cardiac magnetic resonance (CMR) imaging can detect myocardial tissue changes in dilated cardiomyopathy (DCM) without late gadolinium enhancement (LGE). Forty-one DCM patients and 10 healthy volunteers underwent pre- and post-T1...
Susan van Grinsven et al.
Journal of shoulder and elbow surgery, 24(9), 1405-1412 (2015-07-16)
We compared the diagnostic reproducibility and accuracy of musculoskeletal radiologists with orthopaedic shoulder surgeons in 2 large medical centers in assessing magnetic resonance arthrograms (MRAs) of patients with traumatic anterior shoulder instability. Forty-five surgically confirmed MRAs were assessed by 4...
Wendy Oakden et al.
NMR in biomedicine, 28(8), 925-936 (2015-06-09)
Quantitative T2 (qT2), diffusion tensor imaging (DTI), and histology were used to investigate a cervical model of spinal cord injury (SCI) in the rat. While quantitative MRI can significantly increase the specificity in the presence of pathology, it must be...
Nathalie Fretellier et al.
Investigative radiology, 49(12), 766-772 (2014-06-20)
The purposes of this study were to evaluate the risk for analytical interference with gadolinium-based contrast agents (GBCAs) for the colorimetric measurement of serum iron (Fe³⁺) and to investigate the mechanisms involved. Rat serum was spiked with several concentrations of...
Johannes Budjan et al.
European radiology, 24(8), 1835-1844 (2014-05-28)
After allogeneic stem cell transplantation (SCT), a reliable diagnosis of acute graft versus host disease (aGvHD) is essential for an early and successful treatment. It is the aim of this analysis to assess intestinal aGvHD by magnetic resonance imaging (MRI)....
Uwe Lindner et al.
Analytical and bioanalytical chemistry, 407(9), 2415-2422 (2014-12-10)
Hydrophilic interaction chromatography (HILIC) coupled with inductively coupled plasma mass spectrometry (ICP-MS) were optimised for the direct determination of gadolinium-based contrast agents in tap water. In comparison to our previous work, a new developed zwitterionic HILIC column (ZIC-cHILIC) was used...
Anna Axelsson et al.
The lancet. Diabetes & endocrinology, 3(2), 123-131 (2014-12-24)
No medical treatment has been reliably shown to halt or reverse disease progression in hypertrophic cardiomyopathy, but the results of several pilot studies have suggested beneficial effects of angiotensin II receptor blockers on left ventricular hypertrophy and fibrosis, which are...
Parag Amin et al.
AJR. American journal of roentgenology, 202(4), 886-893 (2014-03-26)
The objective of our study was to assess the diagnostic performance of quiescent-interval single-shot (QISS) MR angiography (MRA) at 3 T for the evaluation of chronic lower limb ischemia. For this prospective study, 25 patients referred for lower extremity angiography...
Michinobu Nagao et al.
International heart journal, 55(6), 512-518 (2014-10-15)
The aims of this study were to quantify the geometrical differences in left ventricular (LV) dyssynchrony in patients with heart failure (HF) using cine-tagged MRI, and to investigate the relationship between dyssynchrony and major adverse cardiac events (MACE) in HF.In...
Yongjun Liu et al.
Biomaterials, 33(21), 5363-5375 (2012-04-24)
Theranostic magnetic resonance imaging (MRI) is now receiving a growing interest in imaging-guided drug delivery, monitoring the treatment and personalized administration etc. Theranostic agents are essential for the usage of theranostic MRI. Among different kinds of theranostic agents, gadolinium loaded...
Catherine N Petchprapa et al.
Skeletal radiology, 44(1), 97-105 (2014-10-04)
Assess the diagnostic accuracy of 3-T indirect magnetic resonance arthrography (iMRA) for hip cartilage and labral pathology detection using arthroscopy as the reference standard and compare it to the published performance of direct magnetic resonance arthrography (dMRA). Between 2009 and...
Olaf Dietrich et al.
Magnetic resonance in medicine, 73(3), 1158-1163 (2014-03-19)
To analyze the flip angle dependence and to optimize the statistical precision of a fast three-dimensional (3D) T1 mapping technique based on the variable flip angle (VFA) method. The proposed single flip angle (1FA) approach acquires only a single 3D...
Peter Chhour et al.
ACS nano, 8(9), 9143-9153 (2014-09-05)
Nanoparticles of complex architectures can have unique properties. Self-assembly of spherical nanocrystals is a high yielding route to such systems. In this study, we report the self-assembly of a polymer and nanocrystals into aggregates, where the location of the nanocrystals...
Catherine Do et al.
American journal of physiology. Renal physiology, 307(7), F844-F855 (2014-08-08)
It has been presupposed that the thermodynamic stability constant (K(therm)) of gadolinium-based MRI chelates relate to the risk of precipitating nephrogenic systemic fibrosis. The present study compared low-K(therm) gadodiamide with high-K(therm) gadoteridol in cultured fibroblasts and rats with uninephrectomies. Gadolinium...
Jon A Jacobson et al.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 33(6), 1041-1048 (2014-05-29)
An abnormality of the radial collateral ligament (RCL) in the setting of lateral epicondylitis can indicate a poor clinical outcome; therefore, accurate assessment is important. The purpose of this study was to characterize the proximal RCL attachment, or footprint, as...


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