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Adaptation of dynamic covalent systems of imine constituents to medium change by component redistribution under reversible phase separation.

Journal of the American Chemical Society (2012-07-13)
Nema Hafezi, Jean-Marie Lehn
ABSTRACT

A dynamic covalent library of interconverting imine constituents, dissolved in an acetonitrile/water mixture, undergoes constitutional reorganization upon phase separation induced by a physical stimulus (heat) or a chemical effector (inorganic salt, carbohydrate, organic solvent). The process has been made reversible, regenerating the initial library upon phase reunification. It represents the behavior of a dynamic covalent library upon reversible phase separation and its adaptation to a phase change, with up-regulation in each phase of the fittest constituents by component selection. Finally, the system exemplifies the splitting of a 2D (square) constitutional dynamic network into a 3D (cube) one.

MATERIALS
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Product Description

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