Merck
  • 主页
  • 查找结果
  • Quantification of chemical elements in blood of patients affected by multiple sclerosis.

Quantification of chemical elements in blood of patients affected by multiple sclerosis.

Annali dell'Istituto superiore di sanita (2005-10-26)
Giovanni Forte, Andrea Visconti, Simone Santucci, Anna Ghazaryan, Lorenzo Figà-Talamanca, Stefania Cannoni, Beatrice Bocca, Anna Pino, Nicola Violante, Alessandro Alimonti, Marco Salvetti, Giovanni Ristori
摘要

Although some studies suggested a link between exposure to trace elements and development of multiple sclerosis (MS), clear information on their role in the aetiology of MS is still lacking. In this study the concentrations of Al, Ba, Be, Bi, Ca, Cd, Co, Cr, Cu, Fe, Hg, Li, Mg, Mn, Mo, Ni, Pb, Sb, Si, Sn, Sr, Tl, V, W, Zn and Zr were determined in the blood of 60 patients with MS and 60 controls. Quantifications were performed by inductively coupled plasma (ICP) atomic emission spectrometry and sector field ICP mass spectrometry. When the two groups were compared, an increased level of Co, Cu and Ni and a decrement of Be, Fe, Hg, Mg, Mo, Pb and Zn in blood of patients were observed. In addition, the discriminant analysis pointed out that Cu, Be, Hg, Co and Mo were able to discriminate between MS patients and controls (92.5% of cases correctly classified).

材料
货号
品牌
产品描述

Sigma-Aldrich
乙酸, glacial, ReagentPlus®, ≥99%
Sigma-Aldrich
乙酸, glacial, ACS reagent, ≥99.7%
Sigma-Aldrich
L -还原型谷胱甘肽, ≥98.0%
Sigma-Aldrich
L-半胱氨酸, 97%
Sigma-Aldrich
L -氧化谷胱甘肽, ≥98% (HPLC)
Sigma-Aldrich
乙酸, glacial, puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, 99.8-100.5%
Sigma-Aldrich
L-半胱氨酸, from non-animal source, BioReagent, suitable for cell culture, ≥98%
SAFC
L-半胱氨酸
Sigma-Aldrich
锌, dust, <10 μm, ≥98%
Sigma-Aldrich
L -还原型谷胱甘肽, suitable for cell culture, BioReagent, ≥98.0%, powder
Sigma-Aldrich
锌, granular, 20-30 mesh, ACS reagent, ≥99.8%
Sigma-Aldrich
乙酸, glacial, ≥99.99% trace metals basis
Sigma-Aldrich
乙酸 溶液, suitable for HPLC
Sigma-Aldrich
锌, purum, powder
Sigma-Aldrich
镁, powder, ≥99%
Sigma-Aldrich
乙酸, glacial, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., ≥99.8%
Sigma-Aldrich
L-半胱氨酸, BioUltra, ≥98.5% (RT)
Sigma-Aldrich
镁, turnings, reagent grade, 98%
Sigma-Aldrich
锌, powder, <150 μm, 99.995% trace metals basis
Sigma-Aldrich
L -还原型谷胱甘肽, BioXtra, ≥98.0%
Sigma-Aldrich
铜, powder, <425 μm, 99.5% trace metals basis
Sigma-Aldrich
乙酸, natural, ≥99.5%, FG
Sigma-Aldrich
Raney®-镍, W.R. Grace and Co. Raney® 2800, slurry, in H2O, active catalyst
Sigma-Aldrich
硅, powder, −325 mesh, 99% trace metals basis
Sigma-Aldrich
钙, granular, 99%
Sigma-Aldrich
镁, purum, for Grignard reactions, ≥99.5%, turnings
Sigma-Aldrich
锰, powder, ≥99.9% trace metals basis
Sigma-Aldrich
铜, wire, diam. 1.0 mm, ≥99.9%
Sigma-Aldrich
L-半胱氨酸, ≥97%, FG
Sigma-Aldrich
铜, foil, thickness 0.25 mm, 99.98% trace metals basis