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  • The rise of metal radionuclides in medical imaging: copper-64, zirconium-89 and yttrium-86.

The rise of metal radionuclides in medical imaging: copper-64, zirconium-89 and yttrium-86.

Future medicinal chemistry (2011-04-30)
Oluwatayo F Ikotun, Suzanne E Lapi
摘要

Positron emission tomography, with its high sensitivity and resolution, is growing rapidly as an imaging technology for the diagnosis of many disease states. The success of this modality is reliant on instrumentation and the development of effective and novel targeted probes. Initially, research in this area was focused on what we will define in this article as 'standard' PET isotopes (carbon-11, nitrogen-13, oxygen-15 and fluorine-18), but the short half-lives of these isotopes limit radiopharmaceutical development to those that probe rapid biological processes. To overcome these limitations, there has been a rise in nonstandard isotope probe development in recent years. This review focuses on the biological probes and processes that have been examined, in additiom to the preclinical and clinical findings with nonstandard radiometals: copper-64, zirconium-89, and yttrium-86.

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品牌
产品描述

Sigma-Aldrich
锆, powder, −100 mesh
Sigma-Aldrich
锆, foil, thickness 0.1 mm, 99.98% trace metals basis
Sigma-Aldrich
锆, sponge, ≥99% trace metals basis
Sigma-Aldrich
锆, rod, diam. 6.35 mm, ≥99% trace metals basis
锆, rod, 100mm, diameter 50mm, centerless ground, 99.2%
Sigma-Aldrich
锆, powder, in water, -325 mesh, 99.5% trace metals basis (excluding Hf)
锆, foil, not light tested, 50x50mm, thickness 0.006mm, 99.2%
锆, rod, 1000mm, diameter 1.5mm, 99.2%
锆, rod, 1000mm, diameter 12.7mm, centerless ground, 99.2%
锆, rod, 1000mm, diameter 2.0mm, centerless ground, 99.2%
锆, rod, 1000mm, diameter 3.0mm, centerless ground, 99.2%
锆, rod, 1000mm, diameter 5.0mm, centerless ground, 99.2%
锆, rod, 1000mm, diameter 6.0mm, centerless ground, 99.2%
锆, rod, 1000mm, diameter 9.5mm, centerless ground, 99.2%
锆, rod, 100mm, diameter 1.5mm, 99.2%
锆, rod, 100mm, diameter 12.7mm, centerless ground, 99.2%
锆, rod, 100mm, diameter 19.0mm, centerless ground, 99.2%
锆, rod, 100mm, diameter 2.0mm, centerless ground, 99.2%
锆, rod, 100mm, diameter 3.0mm, centerless ground, 99.2%
锆, rod, 100mm, diameter 5.0mm, centerless ground, 99.2%
锆, rod, 100mm, diameter 6.0mm, centerless ground, 99.2%
锆, rod, 100mm, diameter 9.5mm, centerless ground, 99.2%
锆, rod, 200mm, diameter 1.5mm, 99.2%
锆, rod, 200mm, diameter 12.7mm, centerless ground, 99.2%
锆, rod, 200mm, diameter 19.0mm, centerless ground, 99.2%
锆, rod, 200mm, diameter 2.0mm, centerless ground, 99.2%
锆, rod, 200mm, diameter 3.0mm, centerless ground, 99.2%
锆, rod, 200mm, diameter 5.0mm, centerless ground, 99.2%
锆, rod, 200mm, diameter 6.0mm, centerless ground, 99.2%
锆, rod, 200mm, diameter 9.5mm, centerless ground, 99.2%

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