• 主页
  • 查找结果
  • Mechanistic studies on the reactions of platinum(II) complexes with nitrogen- and sulfur-donor biomolecules.

Mechanistic studies on the reactions of platinum(II) complexes with nitrogen- and sulfur-donor biomolecules.

Dalton transactions (Cambridge, England : 2003) (2012-08-15)
Živadin D Bugarčić, Jovana Bogojeski, Biljana Petrović, Stephanie Hochreuther, Rudi van Eldik
摘要

A brief overview of mechanistic studies on the reactions of different Pt(II) complexes with nitrogen- and sulfur-donor biomolecules is presented. The first part describes the results obtained for substitution reactions of mono-functional Pt(II) complexes with different biomolecules, under various experimental conditions (temperature, pH and ionic strength). In addition, an overview of the results obtained for the substitution reactions of bi-functional Pt(II) complexes, analogous to cisplatin, with biomolecules is given. The last part of this report deals with different polynuclear Pt(II) complexes and their substitution behaviour with different biomolecules. The purpose of this perspective is to improve the understanding of the mechanism of action of Pt(II) complexes as potential anti-tumour drugs in the human body.

材料
货号
品牌
产品描述

Sigma-Aldrich
硫, 99.998% trace metals basis
Sigma-Aldrich
硫, powder, 99.98% trace metals basis
Sigma-Aldrich
铂, wire, diam. 0.5 mm, 99.99% trace metals basis
Sigma-Aldrich
铂, foil, thickness 0.025 mm, 99.9% trace metals basis
Sigma-Aldrich
铂, wire, diam. 0.25 mm, 99.9% trace metals basis
Supelco
硫, PESTANAL®, analytical standard
Sigma-Aldrich
铂, wire, diam. 0.5 mm, 99.9% trace metals basis
Sigma-Aldrich
铂, gauze, 100 mesh, 99.9% trace metals basis
Sigma-Aldrich
铂黑, black, powder, ≤20 μm, ≥99.95% trace metals basis
Sigma-Aldrich
铂, wire, diam. 1.0 mm, 99.9% trace metals basis
Sigma-Aldrich
铂, foil, thickness 0.05 mm, 99.99% trace metals basis
Sigma-Aldrich
铂, powder, 99.995% trace metals basis
Sigma-Aldrich
铂, gauze, 52 mesh, 99.9% trace metals basis
Sigma-Aldrich
铂, nanopowder, <50 nm particle size (TEM)
Sigma-Aldrich
硫, flakes, ≥99.99% trace metals basis
Sigma-Aldrich
铂, wire, diam. 2.0 mm, 99.9% trace metals basis
Sigma-Aldrich
铂, wire, diam. 0.10 mm, 99.99% trace metals basis
Sigma-Aldrich
铂, powder, ≤10 μm, 99.9% trace metals basis
Sigma-Aldrich
铂, wire, diam. 0.25 mm, 99.99% trace metals basis
Sigma-Aldrich
铂黑, fuel cell grade, ≥99.9% trace metals basis
Sigma-Aldrich
铂, wire, diam. 0.076 mm, ≥99.99% trace metals basis
Sigma-Aldrich
铂, foil, thickness 0.125-0.135 mm, 99.9% trace metals basis
Sigma-Aldrich
铂, foil, thickness 1.0 mm, 99.99% trace metals basis
Sigma-Aldrich
铂, foil, thickness 0.25 mm, 99.99% trace metals basis
Sigma-Aldrich
铂, nanopowder, 200 nm particle size (SEM), 99.9% (metals basis)
Sigma-Aldrich
铂, wire, diam. 0.25 mm, thermocouple grade
Sigma-Aldrich
铂, wire, diam. 0.127 mm, 99.99% trace metals basis
Sigma-Aldrich
铂, wire, diam. 1.0 mm, 99.99% trace metals basis
Sigma-Aldrich
铂, wire, diam. 0.20 mm, ≥99.99% trace metals basis
Sigma-Aldrich
铂, wire, diam. 0.127 mm, 99.9% trace metals basis

社交媒体

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

Merck

科研、开发、生产。

作为生命科学行业的全球领先供应商,我们致力于为科研、生物技术开发和生产,以及制药药物疗法开发和生产提供各类解决方案和服务。

© 2021年版权归德国达姆施塔特默克集团(Merck KGaA)及/或其附属公司所有。版权所有。

未经许可,严禁复制本网站上的任何资料。