[Biological activity of tin and immunity].

Sangyo eiseigaku zasshi = Journal of occupational health (1997-01-01)
Y Arakawa
摘要

Tin generates a wide variety of biological activities deriving from its chemical character. In this article, the biological activities of tin compounds are reviewed with a focus on the connection with immunity. The table of contents is as follows: Introduction, 1. Inorganic Tin and Immunity, 2. Organic Tin and Immunity, 2.1. Immunotoxicity, 2.1.1. Immunosuppression, 2.1.2. Thymus atrophy, 2.1.3. Changes in the membrane surface antigens of T cells, 2.2. Antitumor activity, 2.3. Anti-inflammatory action, 2.4. Tolerance manifestation of thymus atrophy, 3. Cellular and Biochemical Aspects of the Activity Manifestation, 3.1. Intracellular distribution of organotins 3.2. Effects on structure and function of Golgi apparatus and endoplasmic reticulum, 3.3. Effects on physical properties of phospholipid membrane, 3.4. Suppressive effects on cell proliferation system, 3.5. Consideration, Conclusion. To sum up this article, tin compounds (especially organotin compounds) act mainly on cellular immune systems and the mechanism appears to be due to their hydrophobicity-dependent intracellular distribution and their action on the phospholipid metabolism including the inhibition of intracellular phospholipid transport between organelles through an impairment of the structure and functions of the Golgi apparatus and the endoplasmic reticulum (ER), and the consequent inhibition of the membrane-mediated signal transduction system leading to DNA synthesis via phospholipid turnover and Ca2+ mobilization.

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锡, ≥99%, powder
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锡, powder, <150 μm, 99.5% trace metals basis
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锡, nanopowder, <150 nm particle size (SEM), ≥99% trace metals basis
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锡, granular, 0.425-2.0 mm particle size, ≥99.5%, ACS reagent
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锡, foil, thickness 0.5 mm, 99.998% trace metals basis
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锡, powder, -100 mesh, 99.99% trace metals basis
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锡, powder, <45 μm particle size, 99.8% trace metals basis
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锡, shot, 99.999% trace metals basis
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锡, powder, 10 μm, 99% trace metals basis
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锡, 99.8%, shot, 3 mm
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锡, wire, diam. 0.5 mm, 99.999% trace metals basis
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锡, foil, thickness 0.127 mm, 99.9%
锡, rod, 100mm, diameter 2.0mm, 99.999+%
锡, foil, 150x150mm, thickness 0.20mm, as rolled, 98.8%
锡, foil, 0.5m coil, thickness 0.009mm, 97.4%
锡, foil, 100x100mm, thickness 0.125mm, as rolled, 98.8%
锡, foil, 100x100mm, thickness 0.125mm, as rolled, 99.99+%
锡, foil, 100x100mm, thickness 0.15mm, as rolled, 98.8%
锡, foil, 100x100mm, thickness 0.15mm, as rolled, 99.99+%
锡, foil, 100x100mm, thickness 0.1mm, as rolled, 98.8%
锡, foil, 100x100mm, thickness 0.1mm, as rolled, 99.95%
锡, foil, 100x100mm, thickness 0.20mm, as rolled, 98.8%
锡, foil, 100x100mm, thickness 0.25mm, as rolled, 98.8%
锡, foil, 100x100mm, thickness 0.25mm, as rolled, 99.99+%
锡, foil, 100x100mm, thickness 0.5mm, as rolled, 98.8%
锡, foil, 100x100mm, thickness 0.5mm, as rolled, 99.99+%
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锡, foil, 100x100mm, thickness 0.75mm, as rolled, 99.99+%
锡, foil, 100x100mm, thickness 1.0mm, as rolled, 98.8%
锡, foil, 100x100mm, thickness 1.0mm, as rolled, 99.99+%

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