FBS - Fetal Bovine Serum & Fetal Calf Serum
Fetal bovine serum (FBS) is the most widely-used growth supplement for cell culture media. When used at appropriate concentrations, it supplies many defined and undefined components that have been shown to satisfy specific metabolic requirements for the culture of cells. FBS is a complex mixture of biomolecules that includes growth factors, proteins, trace elements, vitamins, and hormones that are important for the growth and maintenance of cells in vitro culture. To learn more about how our FBS will work in your application, cell culture media request a sample.
Products
Popular Filters
Fetal Bovine Serum
non-USA origin, sterile-filtered, suitable for cell culture
Fetal Bovine Serum
USA origin, Heat Inactivated, sterile-filtered, suitable for cell culture, suitable for insect cell culture, suitable for hybridoma
Fetal Bovine Serum
USA origin, sterile-filtered, suitable for cell culture, suitable for hybridoma
Fetal Bovine Serum
Heat Inactivated, non-USA origin, sterile-filtered, suitable for cell culture
FBS Superior
Supplemented FBS, EU approved
Fetal Bovine Serum
USA origin, suitable for cell culture
Fetal Bovine Serum
US Origin, EmbryoMax ES Cell Qualified FBS, sterile-filtered, suitable for stem cell culture
Fetal Bovine Serum
USA origin, Charcoal Stripped, sterile-filtered, suitable for cell culture
Fetal Bovine Serum
USA origin, Dialyzed by ultrafiltration against 0.15 M NaCl, sterile-filtered, suitable for cell culture
Fetal Bovine Serum
Australia origin, USDA approved, sterile-filtered, suitable for cell culture
Fetal Bovine Serum
Australia origin, γ-irradiated, sterile-filtered, suitable for cell culture
Fetal Bovine Serum
US Origin, HL-1 Cell Screened FBS, sterile-filtered, suitable for cell culture
Fetal Bovine Serum
USA origin, Heat Inactivated, sterile-filtered, suitable for cell culture
Fetal Bovine Serum
Lipoprotein Deficient Serum from fetal calf
frozen liquid
Fetal Bovine Serum
γ-irradiated, USA origin, sterile-filtered, suitable for cell culture, suitable for hybridoma
Fetal Bovine Serum
Australia origin, suitable for, USDA approved, sterile-filtered, suitable for cell culture, suitable for hybridoma
Fetal Bovine Serum
USA origin, γ-irradiated by SER-TAIN process, sterile-filtered, suitable for cell culture
Fetal Bovine Serum
Fetal Bovine Serum, USA origin, Ultra Low IgG
Fetal Bovine Serum
non-USA origin, γ-irradiated, sterile-filtered, suitable for cell culture
If you are using FBS, media, or reagents from Gibco or Life Technologies/Invitrogen, click here to find our replacement product number.
FBS in Cell Culture
Finding the right FBS has never been easier. As cell culturists, we understand how important it is to find the fetal bovine serum (FBS) that is right for your lab needs and budget. Sustained, cost-effective cell growth and maintenance – along with the consistent culture outcomes that make your experimental results reproducible – depend on choosing and stocking appropriate–quality FBS.
Our FBS selection categories make it easy to choose an FBS product suitable for any cell culture application, based on relevant parameters such as γ-irradiation, geographic origin, suitability for hybridoma or insect culture, need for heat-inactivation, or special application testing.
FBS Classic
FBS products that are suitable for general cell culture applications are collected in the FBS Classic portfolio. These products include serum products that have the following attributes:
- Must pass rigorous testing of up to 48 defined quality release parameters, including endotoxin and hemoglobin
- Dialyzed
- Charcoal-stripped
- 0.1 μm triple-filtered
- USA, USDA, Canada, Australia, and other origin
FBS Premier
For customers using FBS in a biomanufacturing process. Products are manufactured using select raw materials at specialist facilities, frequently employing Single Use Disposal technologies.
FBS Premier products are supported by enhanced levels of documentation, including EDQM Certificates of Suitability. They are also QC tested and released to enhanced levels, especially after being Gamma Irradiated using our validated SER-TAIN process.
- Stringent testing and release procedures based on internationally recognized regulatory guidelines
- Intended Use: For Research or Further Manufacturing
- USA, Australia, and New Zealand origin
FBS Select
Products designated FBS Select are pre-qualified for specialized cell and tissue culture including supplementation of stem cells, cardiomyocytes, and cells cultured for the development of immunotherapeutics. FBS Select products include sera that are:
- EmbryoMax® ES (embryonic stem) cell-qualified
- Mesenchymal stem cell-qualified
- HL-1 cell-screened
- Ultra-low IgG
- Dialyzed by ultrafiltration
- FBS Superior, EU approved
For more information about the FBS Select portfolio of products, click here.
What is Fetal Bovine Serum?
FBS is an important part of your cell culture experiment, and can contain a mixture of growth factors, hormones, proteins, trace elements, vitamins, and more. Have other questions about serum? Discover biological, quality, and regulatory information about sera and other answers to your frequently asked questions, such as:
- How to properly store and thaw serum
- Testing and quality standards
- Why there is lot-to-lot variability in serum
Related Resources
- Article: Fetal Bovine Serum (FBS) – What You Need to Know
Review the basics of using fetal bovine (or calf) serum for cell culture and how sourcing and regulations affect the price of sera for cell-based assays.
- Article: Serum for Cell and Tissue Culture FAQs
Find answers to frequently asked questions (FAQs) about FBS and other serum products, and links to related products.
- Article: Freezing and Thawing FBS and Other Sera
Protect your investment with best practices for storing and thawing FBS and other sera. Sample FBS for validation in your cell culture protocol.
- Article: Frequently Asked Questions About Gamma-Irradiated FBS (Serum) and Other Products for Cell Culture
Find answers to questions (FAQs) about fetal bovine serum (FBS) that is gamma-irradiated by the SER-TAIN™ process. Request a sample of FBS at Sigma-Aldrich.com.
- Article: Bovine Spongiform Encephalopathy (BSE)-Free Fetal Bovine Serum (FBS)
Ensure that bovine products for research and production are free of bovine spongiform encephalopathy. Find BSE-free products including fetal bovine serum (FBS).
- Technical Bulletin: Quality Control Sterility Testing of Serum Products
All test media and processes have been validated and growth promotion testing is performed on each lot of test media.
- Technical Bulletin: Organisms Inactivated by Gamma Irradiation at 25—35 kGy
A list of organisms inactivated by gamma irradiation at 25 - 35 kGy.
- Technical Bulletin: Storing and Thawing Serum
The recommended storage temperature is -10 to -40 °C. At temperatures below -40 °C, the bottles may become brittle resulting in an increased risk of breakage.
- Product Information: Preparation of Charcoal-Stripped and Heat-Inactivated Fetal Calf Serum
Preparation of charcoal-stripped serum.
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