IVD manufacturing

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Hogyan használható a proteináz K a vér DNS extrakciós alkalmazásokban?

A vér DNS extrakciója során a proteináz K, a fehérjék lebontására általánosan használt enzim segíthet a sejt- és magmembránok lebontásában, felszabadítva a DNS-t a sejtekből, amelyek megvédik azt a lebomlástól, és növelik a tisztaságot/hozamot, így alkalmasabbá téve azt a különböző

Fluoreszcens in situ hibridizáció (FISH)

Elérhető fluoreszcens in situ hibridizációs (FISH) eljárások, reagensek és berendezések.

Arany nanorészecskék: Gold Gold Gold Gold: Tulajdonságok és alkalmazások

Az arany (Au) nanorészecskék hangolható optikai és elektronikus tulajdonságokkal rendelkeznek, és számos alkalmazásban használják őket, többek között a fotovoltaikában, az érzékelőkben, a gyógyszeradagolásban és a katalízisben.

Tippek az immunfluoreszcencia protokollokhoz

Az immunfluoreszcencia antitesthez kötött fluoreszcens molekulákat használ a fehérjék lokalizációjára, a módosítások megerősítésére és a fehérjekomplexek vizualizálására.

Sejt-életképességi és proliferációs vizsgálatok

Sejtalapú vizsgálatok sejtproliferációs (BrdU, MTT, WST1), sejtéletképességi és citotoxicitási kísérletek a rák, az idegtudomány és az őssejtkutatás területén történő alkalmazásokhoz.

Guide on How to Use Proteinase K in Different Procedures

Guidelines on use of proteinase K, an enzyme commonly used to degrade proteins, and protect DNA and RNA from degradation in samples.

IVD Lateral Flow – Sample, Conjugate and Absorbent Pad Basics

Choosing lateral flow pad materials is critical to the success of the test. Pads comprise the porous matrices that are used for the sample pad, conjugate pad, and absorbent pad.

Diagnostic Assays Using Leading-Edge Technologies

Discuss challenges and strategies for IVD assay development, commercialization, and utilizing contract manufacturing partners for emerging technologies.

Supply Chain Considerations for IVD Assay

Pandemic underscores importance of strong supply chain management for clinical diagnostic CMO partnerships.

Vet Contract Mfg Partner for Clinical Diagnostics Kit

Contract manufacturing aids IVD device commercialization, providing design, quality, and regulatory assistance for smoother processes.

Tips for Immunofluorescence Protocols

Immunofluorescence uses antibody-conjugated fluorescent molecules for protein localization, modification confirmation, and protein complex visualization.

How Proteinase K Can Be Used in Blood DNA Extraction Applications

In blood DNA extraction, Proteinase K, an enzyme commonly used to degrade proteins, can help break down the cellular and nuclear membranes, releasing DNA from the cells that protect it from degradation and increase purity/yield making it more suitable for

An Introduction to Horseradish Peroxidase (HRP) and Its Applications

Horseradish peroxidase (HRP) is an enzyme used for detecting molecules, degrading toxins, cross-linking proteins, and in diagnostics like lateral flow assays.

Aprotinin Applications in Biotechnology and Pharmaceutical Manufacturing Processes

The Elevate Program offers enhanced quality and documentation attributes for aprotinin, a protease inhibitor used in multiple relevant industries.

Qualitative Tests: Exploring Lateral Flow Assays and Their Applications

Discover qualitative tests with lateral flow assays, including multiplex tests. Learn about their fast, user-friendly applications in diagnostics.

Gold Nanoparticles: Properties and Applications

Gold (Au) nanoparticles have tunable optical and electronic properties and are used in a number of applications including photovoltaics, sensors, drug delivery & catalysis.

MagPrep^® Magnetic for Nucleic Acid Technology

Discover how MagPrep® Silica particles meet essential needs for DNA and RNA nucleic acid purification protocols.

IVD Case Study: CRISPR-based Assay from Mammoth Biosciences

A case study describing how Mammoth Biosciences, a diagnostics company utilizing CRISPR gene editing collaborated with MilliporeSigma for manufacturing scale-up expertise and critical raw material supply chain security to ensure a successful launch and long-term success of their novel SARS

Sensitivity Lateral Flow Diagnostic Assays

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

Fluorescent in situ Hybridization (FISH)

Available Fluorescent in situ hybridization (FISH) procedures, reagents and equipment.

10 Strategic Considerations When Outsourcing Production of In Vitro Diagnostics

The choice of whether to outsource production of an in vitro diagnostic (IVD) or invest and develop in-house capabilities is a foundational business decision. We highlight 10 important benefits of outsourcing and key considerations that should factor into the evaluation

Lateral Flow Test: Design, Materials & Manufacturing Insights

Explore design, materials, & manufacturing of lateral flow tests. Learn about reproducibility, optimization, & Hi-Flow™ Plus membranes for efficient scale-up.

Probumin^® Bovine Serum Albumin (BSA) Powders & Solutions - Frequently Asked Questions

Probumin® BSA is a commonly used bovine serum albumin for buffers, non-specific blocking, protein stabilization and other diagnostic applications. Given the diverse uses of BSA, here are some frequently asked questions and answers about the molecule, formats, methods, and applications.

Proteinase K in Tissue Samples

Pro K aids in disrupting cell membranes for DNA release, crucial for downstream molecular biology techniques.

Multiplex PCR Assay for Damaged DNA

Quality DNA crucial for meaningful data; intact DNA key for successful chromosomal aberration analysis from FFPE tissues.

Elypta's Contract Manufacturing Case Study

Elypta partners with us for standardized GAG quantification kits, meeting growing research assay demands along the regulatory path.

Best Product & Supplier for Proteinase K

Balancing Proteinase K cost with quality and technical support ensures optimal enzyme selection for diverse applications.

Complete Solutions for IVD Chemiluminescent Immunoassay (CLIA/CLEIA) Development

Accelerate your time to market with fit-for-use products which offer the quality, consistency, and documentation necessary for every step of your IVD development and manufacturing needs.

Cell Viability and Proliferation Assays

Cell based assays for cell proliferation (BrdU, MTT, WST1), cell viability and cytotoxicity experiments for applications in cancer, neuroscience and stem cell research.