HomeWebinarsAdvancements in Clinical Nutrition: Targeting Hyper-homocysteinemia with B-vitamins

Advancements in Clinical Nutrition: Targeting Hyper-homocysteinemia with B-vitamins


Date: Tuesday, October 24, 2023
Time: 8:30 am PDT, 11:30 am EDT, 5:30 pm CEST

Numerous chronic illnesses cause a deficiency of B vitamins due to low intake, malabsorption, or polymedications. Deficiency of the B vitamins can cause life-threatening signs and symptoms and worsen disease prognosis. Folate, vitamin B6, and B12 are co-factors needed for cell renewal, methylation, antioxidant capacity of the cell, and normal homocysteine metabolism.

High concentrations of homocysteine are toxic to the body and they predict frailty, morbidities, and all-cause mortality. Lowering homocysteine in chronically and critically ill people requires a combination of the three B vitamins. Methylfolate can lower homocysteine and avoid unmetabolized folic acid in the plasma of chronically and critically ill people.

In this webinar, you will learn about:

  • Folate, B6, and B12 essential nutrients for cell renewal and functions
  • Homocysteine as a friend and a foe
  • Hyperhomocysteinemia, a global nutrition marker in hospitalized patients
  • Avoiding unmetabolized folic acid in critically ill patients
  • Disease history and polymedications: determinants of vitamin deficiency
  • Why we need to lower homocysteine?
  • Effectively lowering homocysteine by the B vitamins


Rima Obeid, Ph.D.

Rima Obeid, Ph.D.

Central Laboratory, Saarland University Hospital

Professor, Department of Clinical Chemistry and Laboratory Medicine

Rima Obeid studied pharmacy and public health. She has a Ph.D. in clinical biochemistry at Saarland University, Germany. She is a recognized researcher in the field of micronutrients and the health of vulnerable groups and is part of a global network of scientists applying methods of evidence-based medicine in the nutrition field. Prof. Obeid conducted and published numerous clinical studies on the role of folate in health and diseases.


Jean-Pierre Knapp

Jean-Pierre Knapp


Senior Scientist, Analytics Quality Services

Jean-Pierre Knapp studied chemistry at the University of Kaiserslautern, Germany. He dedicated most of his extensive professional life to folates, including the development of analytical methods. With his profound analytical expertise, he serves as an elected expert to the SwissMedic and EDQM Expert Group on Chemistry. His folate expertise has also been incorporated into the US Pharmacopeia. He joined our company in 2008 and manages analytical and quality affairs for Arcofolin® and pharmaceutical ingredients.


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