S7507

Sulfamethoxazole

analytical standard

• Synonym(s): 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide, N¹-(5-Methylisoxazol-3-yl)sulfanilamide
• Empirical Formula (Hill Notation): C₁₀H₁₁N₃O₃S
• CAS Number: 723-46-6
• Molecular Weight: 253.28
• Beilstein: 6732984
• EC Number: 211-963-3
• MDL number: MFCD00010546
• PubChem Substance ID: 329824585

Properties

• grade: analytical standard
• Quality Level: 100
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• SMILES string: Cc1cc(NS(=O)(=O)c2ccc(N)cc2)no1
• InChI: 1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13)
• InChI key: JLKIGFTWXXRPMT-UHFFFAOYSA-N

Description

General description

Sulfamethoxazole is a bacteriostatic antibiotic, belonging to the class of sulfonamides. It is widely used in the treatment of pneumocystis, coccidiosis, gastroenteritis, diarrhea, respiratory diseases such as pneumonia, etc.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sulfamethoxazole is used as an analytical reference standard for the quantification of the analyte in milk samples using analytical and microbiological assay technique.

Packaging

10, 25, 100 g

Biochem/physiol Actions

Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase.
Mode of Action: Inhibits folic acid synthesis in prokaryotes.
Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Warning
• Hazard Statements: H317 - H361fd
• Precautionary Statements: P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
• Hazard Classifications: Repr. 2 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves