Solid Phase Extraction (SPE) is a technique designed for rapid and selective sample preparation and purification, prior to chromatographic analysis. The multitude of available phase chemistries can be packed into an array of hardware formats such as individual cartridges, 96-well plates, and QuEChERS tubes (dispersive SPE), which can be processed using a vacuum manifold and dedicated accessories.
Brochure: Solid Phase Extraction Products
Brochure: Supel™ QuE QuEChERS
Brochure: HybridSPE® Phospholipid Removal Technology for Biological Matrices
Application Note: Supel™ DPX HLB tips and Hamilton® - Extraction of opioid drugs from urine
Application Note: Empore™ C18 SPE Disk app note
Application Note: Simplified LC-MS/MS Method for Glyphosate, AMPA and Glyfosinate in oat-based cereals
We offer a diverse range of SPE-phase chemistries and cartridges ideal for many applications including pharmaceutical, clinical, food and beverage, environmental, petrochemical, and agriculture. The phase chemistry selection allows users to screen for the retention and selectivity required to achieve sample preparation objectives.
Our SPE well plates allow users to process up to 96 samples simultaneously for increased reproducibility and throughput, while maintaining excellent recoveries and increased sensitivity. 96-well plates offer compatibility with multi-channel pipettors and automation, and are available with silica-based and polymeric sorbents.
Supel™ Genie Online SPE cartridges offer a sample preparation solution for a seamless workflow from start to finish performed entirely “online” using the LC instrument. Online SPE offers the advantage of eliminating the risk of human error and reduces labor costs by automation of sample preparation.
The “QuEChERS” (Dispersive SPE, dSPE) method has emerged as a popular sample preparation technique in the area of multi-residue pesticide analysis for food and agricultural products. The QuEChERS technique offers the advantage of higher recoveries, accurate results and high sample throughput.
DPX® tips provide an INTip solution for complete sample preparation that can be easily automated to achieve extraction in seconds. HybridSPE® sorbent material is loosely contained within a tip, for selective retention and removal of endogenous phospholipid interferences from biological matrices for LC-MS or LC-MS/MS analysis.
To facilitate sample preparation requirements, we offer a range of accessories including SPE tube components, elution racks, drying attachments, single SPE tube processors, vacuum pump trap kits, disk holders, and vacuum manifolds.