This product is considered a neat or pure liquid. The base molecular weight of this material is 1,228 daltons and the density is 1.095 g/mL. However, this is based on the assumption of 20 ethylene oxide units, 1 sorbitol, and 1 lauric acid. The critical micelle concentration of this detergent is 0.059 mM.
655205
TWEEN® 20
Non-ionic detergent
Synonym(s):
TWEEN® 20, Polysorbate 20, Polyoxyethylene (20) sorbitan monolaurate, PEG(20)sorbitan monolaurate, Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate
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Product Name
TWEEN® 20, Non-ionic detergent used for immunoprecipitation and for the solubilization of membrane-bound proteins.
InChI
1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3
SMILES string
CCCCCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO
InChI key
HMFKFHLTUCJZJO-UHFFFAOYSA-N
description
RTECS - TR7400000
form
liquid
mol wt
~1228
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
pale yellow
refractive index
n20/D 1.468 (lit.)
CMC
59 μM (HLB number 16.7)
solubility
water: 10%
density
1.095 g/mL at 25 °C (lit.)
shipped in
ambient
storage temp.
15-25°C
Quality Level
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Related Categories
1 of 4
This Item | P2287 | P7949 | P1379 |
|---|---|---|---|
| form liquid | form viscous liquid | form viscous liquid | form viscous liquid |
| storage temp. 15-25°C | storage temp. - | storage temp. - | storage temp. - |
| mol wt ~1228 | mol wt ~1228 | mol wt ~1228 | mol wt ~1228 |
| density 1.095 g/mL at 25 °C (lit.) | density 1.095 g/mL at 25 °C (lit.), 1.1 g/cm3 at 25 °C (lit.) | density 1.095 g/mL at 25 °C (lit.) | density 1.095 g/mL at 25 °C (lit.) |
| description RTECS - TR7400000 | description non-ionic | description non-ionic | description non-ionic |
| Quality Level 100 | Quality Level 300 | Quality Level 300 | Quality Level 300 |
Application
Non-ionic detergent
Disclaimer
Toxicity: Standard Handling (A)
General description
Non-ionic detergent used for immunoprecipitation and for the solubilization of membrane-bound proteins (CMC: 59 µM; HLB number: 16.7).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
TWEEN is a registered trademark of Croda International PLC
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
527.0 °F - Pensky-Martens closed cup
flash_point_c
275 °C - Pensky-Martens closed cup
Certificates of Analysis (COA)
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Monika Wimmer et al.
Cell communication and signaling : CCS, 18(1), 61-61 (2020-04-12)
Cutaneous squamous cell carcinomas (cSCC) are the primary cause of premature deaths in patients suffering from the rare skin-fragility disorder recessive dystrophic epidermolysis bullosa (RDEB), which is in marked contrast to the rarely metastasizing nature of these carcinomas in the
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