8.52112
Fmoc-Lys(Me3Cl)-OH
Novabiochem®
Synonym(s):
Fmoc-Lys(Me₃Cl)-OH, N-α-Fmoc-N-ε-trimethyl-N-L-lysine · chloride
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SMILES string
Cl.[N+](CCCC[C@H](N=C([O-])OCC1c2c(cccc2)c3c1cccc3)C(=O)O)(C)(C)C
InChI
1S/C24H30N2O4.ClH/c1-26(2,3)15-9-8-14-22(23(27)28)25-24(29)30-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21;/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H-,25,27,28,29);1H/t22-;/m0./s1
InChI key
XUJRNPVABVHOAJ-FTBISJDPSA-N
product line
Novabiochem®
assay
≥95% (TLC), ≥95.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
amine
storage temp.
2-8°C
Quality Level
1 of 4
This Item | 8.52106 | 8.52065 | 8.52094 |
|---|---|---|---|
| form powder | form powder | form powder | form powder |
| functional group amine | functional group amine | functional group amine | functional group amine |
| assay ≥95% (TLC), ≥95.0% (HPLC) | assay ≥97.0% (HPLC), ≥98% (TLC) | assay ≥95.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC) | assay ≥80.0% (acidimetric), ≥95% (TLC), ≥95.0% (HPLC) |
| product line Novabiochem® | product line Novabiochem® | product line Novabiochem® | product line Novabiochem® |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
General description
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS
Literature references
[1] S. Rothbart, et al. (2012) Methods Enzymol., 512, 107.
Analysis Note
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA1)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
LC/MS: passes test
To see the solvent systems used for TLC of Novabiochem® products please click here.
Other Notes
Legal Information
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.
Protocols
We provide an overview of our available reagents, together with recommendations and details of their use for synthesis of peptides containing post-translationally modified amino acids.
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