I1010
IgA from human colostrum
reagent grade, ≥95%, essentially salt-free, lyophilized powder
Synonym(s):
Human IgA
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5 MG
₹1,26,584.40
25 MG
₹6,46,996.80
About This Item
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conjugate
unconjugated
Quality Level
grade
reagent grade
Assay
≥95%
form
essentially salt-free, lyophilized powder
storage temp.
2-8°C
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This Item | I5506 | I4131 | I2511 |
|---|---|---|---|
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| form essentially salt-free, lyophilized powder | form essentially salt-free, lyophilized powder | form essentially salt-free, lyophilized powder | form buffered aqueous solution |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| grade reagent grade | grade reagent grade | grade reagent grade | grade reagent grade |
| assay ≥95% | assay ≥95% (SDS-PAGE) | assay ≥95% (SDS-PAGE) | assay ≥95% (HPLC) |
| Quality Level 200 | Quality Level 300 | Quality Level 300 | Quality Level 300 |
General description
IgA antibody is secretory antibody and is present abundantly in mucous linings of gastrointestinal, respiratory and genitourinary tracts, tears, colostrum and saliva. Thus secretory IgA contributes to the humoral defense mechanism against the pathogens on mucosal surfaces[1]
Human IgA is purified from pooled normal human colostrum by fractionation and ion-exchange fractionation.
Human IgA is purified from pooled normal human colostrum by fractionation and ion-exchange fractionation.
Application
Purified IgA may be used as a reference antigen, standard, blocking agent or coating protein in a variety of immunoassays including ELISA, dot immunobinding, immunoblotting, immunodiffusion and immunoelectrophoresis. Other applications include starting materials for the preparation of immunogens and solidphase immunoadsorbents. IgA from human colostrum was used as a standard in ELISA (1 mg/ml)[2][3] and gel electrophoresis.[4]
Preparation Note
Reconstitute with buffered saline (150 mM sodium chloride).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Hannah Karen Mina Labayo et al.
EClinicalMedicine, 27, 100561-100561 (2020-10-13)
Norovirus (NV) causes acute gastroenteritis in infants. Humoral and fecal immunoglobulin A (IgA) responses have been correlated with protection against NV; however, the role of breast milk IgA against NV infection and associated diarrhea is still unknown. This study aimed
E Knop et al.
Investigative ophthalmology & visual science, 42(3), 566-574 (2001-02-27)
Mucosa-associated lymphoid tissue (MALT) specifically protects mucosal surfaces. In a previous study of the human conjunctiva, evidence was also found for the presence of MALT in the lacrimal sac. The present study, therefore, aims to investigate its morphology and topographical
Lauri Vehkala et al.
Annals of medicine, 45(8), 501-510 (2013-10-18)
Obesity and type 2 diabetes (T2D) associate with increased oxidative stress. Malondialdehyde acetaldehyde (MAA) adducts have been suggested to be one of the antigenic epitopes in MDA-LDL responsible for the antibody recognition. Our aim was to investigate the associations between
Erick Sánchez-Salguero et al.
Maternal health, neonatology and perinatology, 5, 9-9 (2019-06-18)
Colostrum is the primary source of maternal immunoglobulin A (IgA) for the newborn. IgA participates in protection and regulation mechanisms of the immune response at the neonate's mucosa. Several studies have evaluated infectious diseases and vaccine protocols effects during pregnancy
Susanna R Bidgood et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(37), 13463-13468 (2014-08-30)
IgA is the most prevalent antibody type on mucosal surfaces and the second most prevalent antibody in circulation, yet its role in immune defense is not fully understood. Here we show that IgA is carried inside cells during virus infection
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