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Acids for Laboratory, Analysis & Regulated Applications

Acids bottles

High-purity acids are essential for ensuring reproducible experiments and accurate formulation of new materials and compounds in research and development. They serve as critical reagents or catalysts in chemical synthesis, support qualitative and quantitative analyses in analytical chemistry and pharmacopeia testing, and are widely used in instrumental techniques, including inductively coupled plasma optical emission spectroscopy (ICP-OES), inductively coupled plasma mass spectrometry (ICP-MS), atomic absorption spectrometry (AAS) and as standardized reagents in volumetric titrations.

Our extensive range of acids is offered under three portfolio brands:   

  • Sigma-Aldrich® – Ideal for laboratory use and production-scale workflows
  • Supelco® – Optimized for analytical chemistry and precision testing.
  • SAFC® – Products for biopharmaceutical and pharmaceutical development and manufacturing

Each brand provides acids in a variety of volumes and packaging formats, with comprehensive documentation to meet compliance requirements and support your operational needs.

Emplura® – Basic Grade
Emplura® – Basic Grade

For preparative lab applications and standard production processes.

  • Suitable for numerous basic applications
  • Economical solutions
  • Completely flexible pack sizes
  • Adequate specifications with most common parameters
Learn More
Emparta® – Standard Grade
Emparta® – Standard Grade

A range of high-quality, cost-efficient Bases for routine analytical applications.

  • Standard quality for routine applications
  • Convenient packaging
  • Reliable results
  • Efficient and cost-effective solutions
Learn More

acids (160)

organic acids (146)

inorganic acids (78)

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Trifluoroacetic acid
T6508

Trifluoroacetic acid

ReagentPlus®, 99%

Hydrochloric acid
258148

Hydrochloric acid

37%, ACS reagent

Trifluoroacetic acid
302031

Trifluoroacetic acid

suitable for HPLC, ≥99.0%

Sulfuric acid
258105

Sulfuric acid

ACS reagent, 95.0-98.0%

Acetic acid
695092

Acetic acid

glacial, ACS reagent, ≥99.7%

Nitric acid
438073

Nitric acid

ACS reagent, 70%

Acetic acid
A6283

Acetic acid

glacial, ReagentPlus®, ≥99%

Perchloric acid
244252

Perchloric acid

ACS reagent, 70%

Boron trifluoride-methanol solution
B1252

Boron trifluoride-methanol solution

14% in methanol

Acetic acid (glacial) 100%
1.00063

Acetic acid (glacial)

100%, anhydrous for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Hydrochloric acid
320331

Hydrochloric acid

37%, ACS reagent

Hydrogen chloride solution
345547

Hydrogen chloride solution

4.0 M in dioxane

Hydrochloric acid
1.00317

Hydrochloric acid

37%, for analysis EMSURE® ACS,ISO,Reag. Ph Eur

Hydrofluoric acid
695068

Hydrofluoric acid

ACS reagent, 48%

Chloroplatinic acid hexahydrate
206083

Chloroplatinic acid hexahydrate

ACS reagent, ≥37.50% Pt basis

Nitric acid 65%
1.00456

Nitric acid

65%, for analysis EMSURE® Reag. Ph Eur,ISO

Trifluoroacetic acid
91707

Trifluoroacetic acid

puriss. p.a., suitable for HPLC, ≥99.0% (GC)

Iron(III) chloride hexahydrate
236489

Iron(III) chloride hexahydrate

ACS reagent, 97%

Sulfuric acid 95-97%
1.00731

Sulfuric acid

95-97%, for analysis EMSURE® ISO

Hydriodic acid
210021

Hydriodic acid

57 wt. % in H2O, distilled, stabilized, 99.95%


Organic and Inorganic Acids for Chemical Synthesis and Laboratory Use

Organic and inorganic acids are available in multiple quality grades to support a wide range of chemical synthesis and laboratory workflows. The acids exhibit a minimum purity of ≥95%, making them ideal for general synthesis, standard lab work, and research applications where consistent quality is essential.

ACS-Grade Acids

ACS-grade acids are used for routine chemical synthesis workups, general laboratory applications, and analyses intended for publication.

ReagentPlus® Acids

ReagentPlus® Acids offer a minimum purity of 98.5%, making them ideal for trial synthesis and for preparing intermediate compounds that will undergo further purification after isolation.

Puriss p.a. and Purum-Grade Acids

Puriss p.a. and purum-grade acids are designed for highly sensitive chemical synthesis. These acids meet stringent quality specifications and undergo rigorous metals testing to ensure ultra-high purity and performance.

 A collection of chemical containers, including a blue drum, a white jerrycan, and several brown glass bottles, all labelled with safety information and branding from Supelco.

Acids for Sample Preparation and Classical Analysis

EMPLURA® Acids

EMPLURA® acids are ideal for preparative lab work, cleaning, and production, offering essential specifications at a competitive price.

EMPARTA® Acids for Basic Lab Applications

EMPARTA® acids, meet ACS standards and provide reliable performance at a lower cost for a variety of analytical applications.

EMSURE® Acids for Critical Lab Applications

Our EMSURE® acids represent premium “for analysis (p.a.)” quality for regulated and advanced laboratory applications. Most products meet or exceed ACS, ISO, and Reag. Ph Eur standards. They feature the best and most extensive product specifications available worldwide as well as the widest range of pack sizes and packaging options—from 25 mL glass bottles to 200 L PE barrels—EMSURE® offers unmatched flexibility.

More hazardous EMSURE® acids  are also supplied in our Safebreak bottles  (PE-coated glass) and SafetyCaps, designed for reagents that generate excess pressure. Benefit from application-oriented quality, cost-efficiency, and packaging innovation.

EMSURE® Acids for Pharmacopoeia Analysis

EMSURE® acids are the perfect choice for pharmacopoeia analysis. They meet and exceed global standards including ACS and Reag. Ph Eur, making them ideal for pharmaceutical quality control. These premium-grade reagents simplify audits and reduce validation costs.

Engineered for highly regulated lab environments, EMSURE® acids offer low impurity levels, comprehensive certificates of analysis, and consistent batch-to-batch quality. EMSURE® acids follow European Pharmacopoeia and USP-NF requirements.

A white plastic bottle containing a high purity Hydrochloric acid, labeled with safety information and specifications, featuring a black screw cap.

High Purity Acids for Chromatography and Spectrometry Analysis

LiChropur® High Purity Acids

LiChropur® high purity acids are used for HPLC, GC and LC-MS analysis. These acids are rigorously application-tested to minimize background noise and signal suppression, ensuring reliable results in instrumental analytical chemistry.                                                                                                                   

Suprapur® and Ultrapur® High Purity Acids for ICP-OES, ICP-MS, and AAS

Suprapur® and Ultrapur® high purity acids are ideal for digestion as well as inorganic trace and ultra-trace analysis. The portfolio is optimized to offer a set of acids and bases with lowest inorganic impurities. All products are manufactured under strict quality control aligned with your requirements, supporting sensitive techniques like ICP-OES, ICP-MS, and AAS.

Volumetric Solutions for Titrations

Our Titripur® volumetric solutions and Titrisol® concentrates offer a range of acids in different concentrations for titration. They sourced from high purity raw materials produced and analyzed under high quality standards. The Titripur® solutions are analyzed by our ISO/IEC 17025 accredited laboratory, ensuring reliability and precision. Titripur® solutions offer a seamless digital data transfer to titrator software, enhancing documentation and boosting lab efficiency.

Biopharmaceutical and Pharmaceutical Formulation and Production Products

Achieving consistent quality and regulatory compliance in biopharmaceutical manufacturing requires reliable raw materials and robust documentation. Our SAFC® portfolio provides high-purity process chemicals, solvents, and reagents manufactured under strict cGMP guidelines to support every stage from development and scale-up to commercial production. Through our Emprove® Program, each product is backed by comprehensive documentation that simplifies qualification, risk assessment, and regulatory submissions while ensuring full supply-chain transparency. With our technical expertise and customizable manufacturing options, we help you streamline process development and maintain confidence in your formulation and production workflows. Explore our Emprove® Chemicals portfolio and our complete range of bioprocessing and formulation raw materials to support your pharmaceutical and biopharmaceutical production needs.


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