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66930

Sigma-Aldrich

N-Methyl-D-glucamine

ReagentPlus®, ≥99.0% (T)

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Synonym(s):
1-Deoxy-1-(methylamino)-D-glucitol, Meglumine
Empirical Formula (Hill Notation):
C7H17NO5
CAS Number:
Molecular Weight:
195.21
Beilstein:
385906
EC Number:
MDL number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.22

biological source

synthetic

Quality Level

product line

ReagentPlus®

Assay

≥99.0% (T)

form

powder

optical activity

[α]20/D −16.5±0.5°, c = 2% in H2O

autoignition temp.

~662 °F

mp

126-131 °C
129-131.5 °C (lit.)

solubility

H2O: 0.1 g/mL, clear, colorless

anion traces

chloride (Cl-): ≤50 mg/kg
phosphate (PO43-): ≤5 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤20 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1

InChI key

MBBZMMPHUWSWHV-BDVNFPICSA-N

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General description

N-Methyl-D-glucamine, also known as Meglumine, is a sorbitol-derived amino sugar. It acts as a catalyst in one-pot synthesis of pyranopyrazole derivatives.

Application

N-Methyl-D-glucamine is utilized as:
  • An ion exchange resin due to its high affinity and selectivity for specific ions
  • A buffering agent to remove boron from an aqueous solution

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Water-insoluble polymer?clay nanocomposite ion exchange resin based on N-methyl-D-glucamine ligand groups for arsenic removal.
Urbano BF
Reactive functional Polymers, 72(9), 642-649 (2012)
Polymeric microspheres with N-methyl-d-glucamine ligands for boron removal from water solution by adsorption?membrane filtration process.
Wolska J
Environmental Geochemistry and Health, 32(4), 349-352 (2010)
Separation of aceclofenac and diclofenac in human plasma by free zone capillary electrophoresis using N-methyl-D-glucamine as an effective electrolyte additive
A Zinellu, et al.
European Journal of Pharmaceutical Sciences, 24, 375-380 (2005)
Synthesis of graft adsorbent with N-methyl-D-glucamine for boron adsorption.
Hoshina H
Journal of ion exchange, 18(4), 236-239 (2007)
Meglumine promoted one-pot, four-component synthesis of pyranopyrazole derivatives
RY Guo, et al.
Tetrahedron, 69, 9931-9938 (2013)

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