This product Is expected to be suitable for use as a solvent for recombinant cell culture proteins, such as collagen. However, this item has not been specifically tested for use in cell culture. Note that this is not a sterile product. Currently, a cell culture-tested Acetic Acid is not available.
A6283
Acetic acid
glacial, ReagentPlus®, ≥99%
Acetic acid
1 of 3 reviewers received a sample product or took part in a promotion
Synonym(s):
Glacial acetic acid
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| Size/SKU | Availability | Price |
|---|---|---|
500 mL | Estimated to ship TODAYfromSchnelldorf Distribution | €43.40 |
1 L | Estimated to ship TODAYfromSchnelldorf Distribution | €70.50 |
2.5 L | Estimated to ship on13 July 2026fromSchnelldorf Distribution | €141.00 |
About This Item
Linear Formula:
CH3CO2H
CAS Number:
Molecular Weight:
60.05
UNSPSC Code:
12352106
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-580-7
Beilstein/REAXYS Number:
506007
MDL number:
Assay:
≥99%
Form:
liquid
vapor density
2.07 (vs air)
Quality Segment
product line
ReagentPlus®
assay
≥99%
form
liquid
autoignition temp.
800 °F
expl. lim.
16 %, 92 °F, 4 %, 59 °F
refractive index
n20/D 1.371 (lit.)
pH
2.5 (20 °C, 50 g/L)
bp
117-118 °C (lit.)
mp
16.2 °C (lit.)
solubility
alcohol: miscible(lit.), carbon disulfide: insoluble(lit.), glycerol: miscible(lit.), water: miscible(lit.)
density
1.04 g/mL at 25 °C (lit.)
storage temp.
room temp
SMILES string
[F2C(F2C)13F3C]C(O)=O
InChI
1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
InChI key
QTBSBXVTEAMEQO-UHFFFAOYSA-N
General description
Acetic acid is an aliphatic organic acid. It is a hygroscopic, corrosive liquid with a vinegar-like odor. It can be synthesized by oxidizing acetaldehyde in the presence of manganese or cobalt salts. It is utilized for synthesizing acetic anhydride, cellulose acetate and acetic esters. Its impact on the degradation of historic paper has been analyzed.
Application
Acetic acid (AcOH) can be used as:
Acetic acid can also be used in the following:
- A reaction solvent in many organic reactions such as bromination, hydrolysis, solvolysis, reductions, and hydrogenations.
- A reagent in the protonolysis of organometallic compounds.
- An acetylating agent for the acetylation of electron-rich aromatic compounds.
- A catalyst to synthesize di(indolyl)methanes by the condensation reaction of indole and aromatic aldehydes.
- A solvent system to prepare 3,4-dihydropyrimidin-2(1H)-one derivative via Biginelli reaction of aromatic aldehydes, 1,3-dicarbonyl compounds, and urea in the presence of a boric acid catalyst.
Acetic acid can also be used in the following:
- Manganese(III) acetate/AcOH catalytic system is used in the conversion of alkenes to lactones.
- Iron salts/AcOH is used to oxidize 2-methylnaphthalene to 2-methyl-1-naphthol in the presence of H2O2.
Features and Benefits
- Good stability towards many reagents
- Excellent solubility of organic compounds in this reagent
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥99% | assay ≥99.8% | assay ≥99.5% | assay - |
| Quality Level 200 | Quality Level 100 | Quality Level 300, 400 | Quality Level 200 |
| form liquid | form liquid | form liquid | form liquid |
| storage temp. room temp | storage temp. - | storage temp. - | storage temp. 15-25°C |
| pH 2.5 (20 °C, 50 g/L) | pH 2.4 (60.05 g/L) | pH 2.5 (20 °C, 50 g/L) | pH - |
| solubility alcohol: miscible(lit.), glycerol: miscible(lit.), carbon disulfide: insoluble(lit.), water: miscible(lit.) | solubility - | solubility - | solubility - |
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
102.2 °F - closed cup
flash_point_c
39 °C - closed cup
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Is this suitable as solvent for recombinant cell culture proteins (e.g., collagen C5533-5MG)?
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what is the molarity of acetic acid product number A6283
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The product's concentration is 17.3 mol/liter, corrected for the lot-specific purity shown on its Certificate of Analysis.
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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is ReagentPlus (acid acetic) suitable for HPLC - UV ? as "100%, for HPLC LiChropur"
1 answer-
With a guaranteed purity of ≥98.5%, this product is suitable for general laboratory use, including trial synthesis and preparation. Although not specifically designed for analytical applications, it can be utilized in such contexts. However, it is recommended to use a solvent specifically suitable for HPLC or analytical grade applications.
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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