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Cell signaling

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Vitronectin is a glycoprotein present in plasma and tissues. Together with fibronectin, vitronectin is one of the major cell adhesion proteins in plasma.
Myelin Associated Glycoprotein (MAG)
Myelin Associated Glycoprotein (MAG) is a type I transmembrane glycoprotein containing five Ig-like domains in its extracellular domain. It is an adhesion molecule belonging to the immunoglobin superfamily.
Cholesterol Biosynthesis Regulation
The amount of cholesterol that is synthesized in the liver is tightly regulated by dietary cholesterol levels. LDL receptors regulate the cellular transport of lipid rich low density lipoprotein (LDL) particles.
Calcitonin Gene-Related Peptides
Sigma-Aldrich offers many products related to calcitonin gene-related peptides for your research needs.
Vimentin is an intermediate filamentous cytosketetal protein found in cells of mesenchymal origin. Vimentin typically exists as a coiled-coil dimer that interacts with another dimers to form a tetrameric complex that forms cytoskeletal protein sheets
Myosins are a family of ATP-dependent motor proteins. Myosin II is the major contractile protein involved in eukaryotic muscle contraction by “walking” along actin microfilaments of the sarcomere
Tropomyosin together with troponin, regulate the binding of myosin to actin. Tropomyosin is a dimeric coiled-coil protein forming continuous polymers along the myosin-binding groove of actin. Varoius tropomyosin isoforms help to confer structure and function to actins in the
Spectrin is the major component of the protein network, which covers the cytoplasmic surface of vertebrate, erythrocyte membranes. It is a high molecular weight heterodimer, composed of two subunits (molecular weights of approximately 230 kDa and 250 kDa)
Enzyme Explorer Product Application Index for Elastase. Leukocyte elastase is a 29KDa serine endoprotease of the Proteinase S1 Family. It exists as a single 238 amino acid-peptide chain with four disulfide bonds.
Mitochondrial Stress and ROS
Oxidative stress is mediated, in part, by reactive oxygen species produced by multiple cellular processes and controlled by cellular antioxidant mechanisms such as enzymatic scavengers or antioxidant modulators. Free radicals, such as reactive oxygen species, cause cellular damage via cellular.
Insulin-like Growth Factors (IGF)
Insulin-like Growth Factors (IGF)
Interleukin Family (IL)
The Interleukins comprise a disparate group of cytokines and growth factors that are produced by and released from leukocytes. Interleukin-1β (1L-1β) is released primarily from stimulated macrophages and monocytes and plays a key role in inflammatory and immune responses and
VEGF Pathway
Read review on VEGF signaling pathway (Vascular endothelial growth factor (VEGF)/VEGF receptor) and find related products.
N-Linked Glycans Overview
N-linked glycosylation, modification, and degradation
c-Src kinase (Csk)
The C-terminal c-Src kinase (Csk) is a 50-kDa cytosolic tyrosine kinase expressed in all examined cell types
We offers many products related to neuropeptidases for your research needs.
Caspases Inhibitors and Activators
Agents reported to activate cellular caspases include chemotherapeutic drugs, TNF receptor agonists, and other enzymes. Inhibitors of apoptosis were the first identified endogenous caspase inhibitors.
Nitric Oxide Synthases
We offer many products related to nitric oxide synthases for your research needs.
Phosphoprotein Phosphatases (Serine/Threonine)
We offers many products related to phosphoprotein phosphatases (Serine/Threonine) for your research needs.
Cyclic Nucleotide-Gated (CNG) and Hyperpolarization Activated Cyclic Nucleotide-Gated (HCN) Channels
We offers many products related to CNG and HCN channels for your research needs.
Phospholipase A2
Phospholipase A2 (PLA2) designates a class of enzymes that hydrolyze the sn-2 ester of glycerophospholipids to produce a fatty acid and a lysophospholipid. It has become clear that some of these enzymes liberate arachidonic acid in mammalian cells for the
Chloride Channels
We offer many products related to chloride channels for your research needs.
Angiotensin Receptors
We offer many products related to angiotensin receptors for your research needs.
Phospholipase C
The hydrolysis of a minor membrane phospholipid, phosphatidylinositol 4,5-bisphosphate (PIP2) by a specific phospholipase C (PLC) is one of the earliest key events in the regulation of various cell functions by more than 100 extracellular signaling molecules.
Phospholipase D
Phosphatidylcholine (PC)-specific phospholipase D (PLD) enzymes catalyze the hydrolysis of PC to generate choline and phosphatidic acid. These enzymes belong to a superfamily of phosphatidyltransferases with a characteristic unique duplicated catalytic domain motif, the PLD or " HKD"
Transient Receptor Potential Channels
We offer many products related to transient receptor potential channels for your research needs.
P2 Receptors: P2Y G-Protein Family Overview
Surface receptors for extracellular nucleotides are called P2 receptors. Learn more about P2Y G protein-coupled receptors, GPCRs, and ionotropic P2 receptors (P2X ligand-gated ion channels, LGICs).
Lipopolysaccharides for Research – Structure, Function & Applications
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
Calcium Channels
We offers many products related to calcium channels for your research needs.
The extracellular signal regulated kinase (ERK1 and ERK2) pathways are activated by mitogens and play an important role in controlling cell growth and differentiation.
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