Organic reaction toolbox

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The Biginelli Reaction is an acid-catalyzed, three-component reaction between an aldehyde, b-ketoester, and urea that produces tetrahydropyrimidones, which have potential pharmaceutical applications.

Acid and Base Chart — Table of Acids & Bases

Acid and base chart lists the strength of acids and bases (strongest to weakest) in order. Simple to use laboratory reference chart for scientists, researchers and lab technicians.

Greener Methods: Catalytic Amide Bond Formation

We are proud to offer a number of products used in catalytic amidation technology.

Synthia™ Organic Retrosynthesis Software - Resources

Learn more about Synthia™ Organic Retrosynthesis Software and view a list of publications.

Friedel–Crafts Acylation

Friedel-Crafts acylation with Lewis acid catalysts forms monoacylated products via electrophilic aromatic substitution of arenes.

Schlenk Type Glassware

Versatile system for chemical reactions, extractions, and transfers of solids and liquids in laboratories.

Single-Electron Oxidation Transformations

Review SET mechanism in photoredox catalysis for sustainable reactions and rearrangement of oxaziridines.

Fries Rearrangement

Quantum dots (QDs): Semiconductor nanoparticles with diverse applications including displays, lighting, and biomedical imaging.

Visible-Light-Mediated Reactions under Mild Conditions

This review provides a summary of recent approaches in developing green methods for visible-light-mediated reactions that operate under mild conditions and avoid the need for toxic transition-metal catalysts or harsh reaction conditions.

Baeyer-Villiger Oxidation Reaction

The Baeyer-Villiger oxidation is the oxidative cleavage of a carbon-carbon bond adjacent to a carbonyl, which converts the ketones to esters and the cyclic ketones to lactones.

Inverse Electron Demand Diels-Alder Reactions

Inverse electron demand Diels-Alder reactions enable total synthesis of natural products with heteroaromatic ring systems.

Knoevenagel Condensation Reaction

Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.

1-hydrosilatrane

As a versatile hydride reagent, 1-hydrosilatrane can be used in reduction reactions to synthesize alcohols, amines, their chiral counterparts, and esters from aldehydes/ketones.

Sure/Seal™ Packaging System

Our Sure/Seal air-sensitive and anhydrous packaging system has been improved to incorporate larger puncture are and new elastomer liner which has greater sealing properties.

Protected Carbohydrate Building Blocks for More Efficient Syntheses

Carbohydrates and their biologically active glycoconjugate analogs are emerging as an important class of biomolecules.

Chiral Phosphoric Acids: Versatile Organocatalysts with Expanding Applications

TRIP and TiPSY Chiral Phosphoric Acid Catalysts

PI and PSI – Chiral phosphorus incorporation harnessing the potential of P(V)

PI and PSI reagents are a platform of phosphate-based reagents for phosphorylation and phosphothiolation of nucleotides and peptides developed by the Baran lab.

Unnatural Amino Acids for Peptide Synthesis

Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.

Aldol Condensation Reaction

The aldol condensation reaction is an organic reaction introduced by Charles Wurtz, who first prepared the β-hydroxy aldehyde from acetaldehdye in 1872.

VSEPR Chart | Valence Shell Electron Pair Repulsion Theory

Use our handy VSEPR chart to find the 3-D geometric VSEPR shapes of molecules and ions and learn about VSEPR theory and shapes.

Asymmetric Catalysis with Chiral Oxazaborolidinium Ions (COBIs)

Learn about the applications of chiral oxazaborolidinium ions (COBIs) as Lewis acid catalysts in different asymmetric reactions such as cyclopropanation, epoxidation, and radical reactions along with details of their catalytic action.

Recent Advances in the Catalytic Transformations

This article details the latest progress in synthesizing alkylsulfonyl fluorides through different approaches that utilize photoredox catalysis, electrocatalysis, transition-metal catalysis, and organocatalysis. The alkylsulfonyl fluorides thus prepared could be utilized further in sulfur(VI) fluoride exchange (SuFEx) click reactions.

Spirocyclic Building Blocks for Scaffold Assembly

Spirocyclic modules containing four-membered rings are currently of growing interest to discovery chemists.

Periodic Table of the Elements

Download printable Periodic Table with element names, atomic mass, and numbers for quick reference and lab use.

Pressure Conversion Table

Pressure converter aids in quick unit conversions for pressure measurements in laboratory, classroom, or field settings.

Diels–Alder Reaction

The Diels–Alder reaction is the reaction between a conjugated diene and an alkene (dienophile) to form unsaturated six-membered rings. It is also referred to as a cycloaddition.

Selecting Orthogonal Building Blocks

Novabiochem® offers orthogonally protected amino acids for peptide synthesis, including cyclic and branched peptides.