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The molybdenum cofactor.

The Journal of biological chemistry (2013-03-30)
Ralf R Mendel
ABSTRACT

The transition element molybdenum needs to be complexed by a special cofactor to gain catalytic activity. Molybdenum is bound to a unique pterin, thus forming the molybdenum cofactor (Moco), which, in different variants, is the active compound at the catalytic site of all molybdenum-containing enzymes in nature, except bacterial molybdenum nitrogenase. The biosynthesis of Moco involves the complex interaction of six proteins and is a process of four steps, which also require iron, ATP, and copper. After its synthesis, Moco is distributed, involving Moco-binding proteins. A deficiency in the biosynthesis of Moco has lethal consequences for the respective organisms.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Molybdenum, foil, thickness 1.0 mm, ≥99.9% trace metals basis
Sigma-Aldrich
Molybdenum, foil, thickness 0.025 mm, ≥99.9% trace metals basis
Sigma-Aldrich
Molybdenum, foil, thickness 0.1 mm, ≥99.9% trace metals basis
Molybdenum, tube, 100mm, outside diameter 1.0mm, inside diameter 0.7mm, wall thickness 0.15mm, 99.9%
Molybdenum, foil, light tested, 25x25mm, thickness 0.005mm, 99.9%
Molybdenum, tube, 500mm, outside diameter 3.15mm, inside diameter 2.39mm, wall thickness 0.38mm, 99.9%
Molybdenum, foil, light tested, 29x500mm, thickness 0.0712mm, annealed, 99.9%
Molybdenum, rod, 100mm, diameter 3.0mm, centerless ground, 99.9%
Molybdenum, rod, 50mm, diameter 25mm, centerless ground, 99.9%
Molybdenum, foil, not light tested, 100x100mm, thickness 0.007mm, 99.9%
Molybdenum, rod, 200mm, diameter 10.0mm, centerless ground, 99.9%
Molybdenum, foil, not light tested, 100x100mm, thickness 0.01mm, 99.9%
Molybdenum, tube, 50mm, outside diameter 6.4mm, inside diameter 4.6mm, wall thickness 0.9mm, 99.9%
Molybdenum, rod, 100mm, diameter 8.0mm, centerless ground, 99.9%
Molybdenum, microfoil, disks, 25mm, thinness 1.0μm, specific density 1022μg/cm2, permanent mylar 3.5μm support, 99.9%
Molybdenum, wire reel, 1m, diameter 0.013mm, hard, 99.8+%
Molybdenum, foil, light tested, 50x50mm, thickness 0.009mm, 99.9%
Molybdenum, rod, 1000mm, diameter 6.0mm, centerless ground, 99.9%
Molybdenum, foil, not light tested, 100x100mm, thickness 0.005mm, 99.9%
Molybdenum, tube, 200mm, outside diameter 1.0mm, inside diameter 0.7mm, wall thickness 0.15mm, 99.9%
Molybdenum, pellets, 50g, max. size 10mm, 99.9%
Molybdenum, rod, 100mm, diameter 12mm, centerless ground, 99.9%
Molybdenum, foil, not light tested, 150x150mm, thickness 0.05mm, annealed, 99.9%
Molybdenum, mesh, 150x150mm, nominal aperture 0.44mm, wire diameter 0.07mm, 50 wires/inch, open area 67%, plain weave mesh
Molybdenum, foil, 100x100mm, thickness 0.25mm, annealed, polished on both sides, 99.9%
Molybdenum, rod, 1000mm, diameter 8.0mm, centerless ground, 99.9%
Molybdenum, foil, light tested, 50x50mm, thickness 0.01mm, 99.9%
Molybdenum, foil, not light tested, 50x50mm, thickness 0.009mm, 99.9%
Molybdenum, wire reel, 0.5m, diameter 1.25mm, annealed, 99.95%
Molybdenum, tube, 1000mm, outside diameter 1.0mm, inside diameter 0.7mm, wall thickness 0.15mm, 99.9%