sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

268283

Sigma-Aldrich

Nickel, powder, <1 μm, 99.8% trace metals basis

357634

Sigma-Aldrich

Nickel, wire, diam. 0.25 mm, ≥99.9%

267058

Sigma-Aldrich

Nickel, wire, diam. 0.5 mm, ≥99.99% trace metals basis

221678

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

510041

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 4200, slurry, in H₂O, active catalyst

203904

Sigma-Aldrich

Nickel, powder, <150 μm, 99.99% trace metals basis

510068

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 3202, slurry, in H₂O, active catalyst

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

268259

Sigma-Aldrich

Nickel, foil, thickness 0.125 mm, ≥99.9%

GF18961960

Nickel, tube, 200mm, outside diameter 1.3mm, inside diameter 1.1mm, wall thickness 0.1mm, hard, 99.5%

GF71418416

Nickel, tube, 200mm, outside diameter 1.57mm, inside diameter 0.63mm, wall thickness 0.47mm, hard, 99.5%

GF26360928

Nickel, foil, 25mm disks, thickness 0.0075mm, 99.95%

GF45528206

Nickel, foil, 15mm disks, thickness 0.5mm, as rolled, 100%

GF25597390

Nickel, foil, 15mm disks, thickness 0.05mm, as rolled, 99.99+%

GF65882874

Nickel, foil, 15mm disks, thickness 0.0075mm, 99.9%

GF25904842

Nickel, tube, 100mm, outside diameter 7.11mm, inside diameter 6.57mm, wall thickness 0.27mm, hard, 99.5%

GF22416320

Nickel, wire reel, 20m, diameter 0.15mm, as drawn, 99%

GF25814077

Nickel, foil, 15mm disks, thickness 0.125mm, annealed, 99%

GF12414653

Nickel, tube, 1000mm, outside diameter 1.0mm, inside diameter 0.8mm, wall thickness 0.1mm, hard, 99.5%

GF38787889

Nickel, foil, 15mm disks, thickness 0.125mm, as rolled, 100%

GF87663303

Nickel, tube, 1000mm, outside diameter 2.5mm, inside diameter 2mm, wall thickness 0.25mm, hard, 99.5%

GF05063082

Nickel, foil, 25mm disks, thickness 0.075mm, annealed, 99%

GF53303396

Nickel, foil, 25mm disks, thickness 0.007mm, 99.95%

GF96107542

Nickel, tube, 100mm, outside diameter 5.5mm, inside diameter 5mm, wall thickness 0.25mm, hard, 99.5%

GF57654939

Nickel, tube, 200mm, outside diameter 0.78mm, inside diameter 0.2mm, wall thickness 0.29mm, as drawn, 99.5%

GF49702406

Nickel, foil, light tested, 50x50mm, thickness 0.0075mm, 99.95%

GF91494355

Nickel, foil, 25x25mm, thickness 0.25mm, annealed, 99.98%

GF41108925

Nickel, foil, 150x150mm, thickness 0.5mm, as rolled, 99.99+%

GF97678995

Nickel, wire reel, 10m, diameter 0.25mm, as drawn, 99.99+%