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Merck

Cell biology of molybdenum.

BioFactors (Oxford, England) (2009-07-23)
Ralf R Mendel
ABSTRACT

The transition element molybdenum (Mo) is an essential micronutrient that is needed as catalytically active metal during enzyme catalysis. In humans four enzymes depend on Mo: sulfite oxidase, xanthine oxidoreductase, aldehyde oxidase, and mitochondrial amidoxime reductase. In addition to these enzymes, plants harbor a fifth Mo-enzyme namely nitrate reductase. To gain biological activity and fulfill its function in enzymes, Mo has to be complexed by a pterin compound thus forming the molybdenum cofactor. This article will review the way that Mo takes from uptake into the cell, via formation of the molybdenum cofactor and its storage, up to the final insertion of the molybdenum cofactor into apometalloenzymes.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Molybdenum, foil, thickness 0.025 mm, ≥99.9% trace metals basis
Sigma-Aldrich
Molybdenum, foil, thickness 0.1 mm, ≥99.9% trace metals basis
Sigma-Aldrich
Molybdenum, foil, thickness 1.0 mm, ≥99.9% trace metals basis
Molybdenum, foil, light tested, 50x50mm, thickness 0.009mm, 99.9%
Molybdenum, foil, light tested, 25x25mm, thickness 0.05mm, annealed, 99.9%
Molybdenum, foil, 1m coil, thickness 0.008mm, 99.9%
Molybdenum, foil, 50mm disks, thickness 0.30mm, annealed, 99.9%
Molybdenum, foil, 6mm disks, thickness 0.007mm, 99.9%
Molybdenum, foil, 5m coil, thickness 0.04mm, coil width 0.7mm, annealed, 99.9%
Molybdenum, foil, 6mm disks, thickness 0.006mm, 99.9%
Molybdenum, foil, 6mm disks, thickness 0.03mm, annealed, 99.9%
Molybdenum, rod, 200mm, diameter 10.0mm, centerless ground, 99.9%
Molybdenum, rod, 100mm, diameter 4.0mm, centerless ground, 99.9%
Molybdenum, tube, 100mm, outside diameter 1.0mm, inside diameter 0.7mm, wall thickness 0.15mm, 99.9%
Molybdenum, rod, 50mm, diameter 5.0mm, 99.98%
Molybdenum, foil, not light tested, 100x100mm, thickness 0.005mm, 99.9%
Molybdenum, foil, light tested, 29x500mm, thickness 0.0712mm, annealed, 99.9%
Molybdenum, foil, light tested, 25x25mm, thickness 0.004mm, 99.9%
Molybdenum, microfoil, disks, 25mm, thinness 1.0μm, specific density 1022μg/cm2, permanent mylar 3.5μm support, 99.9%
Molybdenum, insulated wire, 20m, conductor diameter 0.125mm, insulation thickness 0.012mm, polyimide insulation, 99.95%
Molybdenum, foil, not light tested, 50x50mm, thickness 0.007mm, 99.9%
Molybdenum, foil, light tested, 25x25mm, thickness 0.009mm, 99.9%
Molybdenum, foil, light tested, 25x25mm, thickness 0.005mm, 99.9%
Molybdenum, wire reel, 100m, diameter 0.2mm, as drawn, 99.95%
Molybdenum, foil, not light tested, 50x50mm, thickness 0.006mm, 99.9%
Molybdenum, rod, 100mm, diameter 12mm, centerless ground, 99.9%
Molybdenum, foil, not light tested, 50x50mm, thickness 0.009mm, 99.9%
Molybdenum, foil, light tested, 50x50mm, thickness 0.006mm, 99.9%
Molybdenum, pellets, 100g, max. size 10mm, 99.9%
Molybdenum, mesh, 150x150mm, nominal aperture 0.44mm, wire diameter 0.07mm, 50 wires/inch, open area 67%, plain weave mesh