ACVR2B
activin A receptor, type IIB
Sinonimi:
ACTRIIB, ActR-IIB, HTX4
Specie:
Human ACVR2B (93), Mouse Acvr2b (11481), Rat Acvr2b (25366), Horse ACVR2B (100053588), domestic cat ACVR2B (101086087), dog ACVR2B (485590), naked mole-rat Acvr2b (101711703), Zebrafish acvr2b (30457), chicken ACVR2B (374213), domestic guinea pig Acvr2b (100722791) ...Più
ID UniProtKB:
ID gene:
- Human(93) Summary: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008]
- Mouse(11481) activin receptor IIB
- Rat(25366) activin A receptor, type IIB
- Horse(100053588) activin A receptor, type IIB
- domestic cat(101086087) activin A receptor, type IIB
- dog(485590) activin A receptor, type IIB
- naked mole-rat(101711703) activin A receptor, type IIB
- Zebrafish(30457) activin receptor IIb
- chicken(374213) activin A receptor, type IIB
- domestic guinea pig(100722791) activin A receptor, type IIB
- sheep(443156) activin A receptor, type IIB
- cow(282131) activin A receptor, type IIB
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ELISA
Numero di prodotto
Descrizione
Specie
Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti ACVR2B Antibody, clone 23GB620, Rabbit Monoclonal, clone 23GB620, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
immunofluorescence
western blot
western blot
Anti-Activin Receptor IIB antibody produced in goat, affinity isolated antibody,
Reattività con
human
Applicazione
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ACVR2B antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, guinea pig, horse, human, rat, sheep
Applicazione
western blot
Monoclonal Anti-ACVR2B antibody produced in mouse, clone 1C11, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
western blot
Anti-ACVR2B (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
western blot