ALPL
alkaline phosphatase, liver/bone/kidney
Sinonimi:
AP-TNAP, APTNAP, HOPS, TNAP, TNSALP
Specie:
Human ALPL (249), Mouse Alpl (11647), Rat Alpl (25586), naked mole-rat Alpl (101725910), Zebrafish alpl (393982), chicken ALPL (396317), sheep ALPL (101123195), cow ALPL (280994), domestic cat ALPL (727689), domestic guinea pig Alpl (100718683)
ID UniProtKB:
ID gene:
- Human(249) Summary: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
- Mouse(11647) alkaline phosphatase, liver/bone/kidney
- Rat(25586) alkaline phosphatase, liver/bone/kidney
- naked mole-rat(101725910) alkaline phosphatase, liver/bone/kidney
- Zebrafish(393982) alkaline phosphatase, liver/bone/kidney
- chicken(396317) alkaline phosphatase, liver/bone/kidney
- sheep(101123195) alkaline phosphatase, liver/bone/kidney
- cow(280994) alkaline phosphatase, liver/bone/kidney
- domestic cat(727689) alkaline phosphatase, liver/bone/kidney
- domestic guinea pig(100718683) alkaline phosphatase, liver/bone/kidney
- dog(403548) alkaline phosphatase, liver/bone/kidney
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Numero di prodotto
Descrizione
Specie
Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anticorpo monoclonale ANTI-FLAG® M2, clone M2, purified immunoglobulin, buffered aqueous glycerol solution,
Reattività con
all
Applicazione
ELISA
Anti-Alkaline Phosphatase (ALPL) antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
western blot
Monoclonal Anti-ALPL antibody produced in mouse, clone 2F4, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Anti-ALPL antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-ALPL antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Small Molecule - Inhibitor
Numero di prodotto
Descrizione
Specie
Kits
Numero di prodotto
Descrizione
Specie