BAX
BCL2-associated X protein
Sinonimi:
BCL2L4
Specie:
Human BAX (581), Mouse Bax (12028), Rat Bax (24887), domestic cat BAX (493837), dog BAX (403523), cow BAX (280730), sheep BAX (443059), Goat BAX (100846984), naked mole-rat Bax (101713575), domestic guinea pig Bax (100730890)
ID UniProtKB:
ID gene:
- Human(581) Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
- Mouse(12028) BCL2-associated X protein
- Rat(24887) Bcl2-associated X protein
- domestic cat(493837) BCL2-associated X protein
- dog(403523) BCL2-associated X protein
- cow(280730) BCL2-associated X protein
- sheep(443059) BCL2-associated X protein
- Goat(100846984) BCL2-associated X protein
- naked mole-rat(101713575) BCL2-associated X protein
- domestic guinea pig(100730890) BCL2-associated X protein
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-Bax Antibody, NT, aa3-16 hBax protein, clone 2D2, clone 2D2, Chemicon®, from mouse,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Bax Antibody, clone 1C7, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Bax Antibody, clone 6A7, from mouse,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Bax (NT) Antibody, from rabbit,
Reattività con
bovine, canine, chimpanzee, feline, human, rhesus monkey
Applicazione
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-BAX antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Cell Lines
Proteins
Numero di prodotto
Descrizione
Specie
BAX, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
esiRNA
Numero di prodotto
Descrizione
Specie