Passa al contenuto
Merck

CASP10

caspase 10, apoptosis-related cysteine peptidase

Sinonimi:
ALPS2, FLICE2, MCH4
Specie:
ID UniProtKB:
ID gene:
  • Human(843) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
  • cow(100848685) caspase 10, apoptosis-related cysteine peptidase
  • chicken(424081) caspase 10, apoptosis-related cysteine peptidase
  • domestic cat(101085995) caspase 10, apoptosis-related cysteine peptidase
  • naked mole-rat(101712620) caspase 10, apoptosis-related cysteine peptidase
  • domestic guinea pig(100717714) caspase 10, apoptosis-related cysteine peptidase
  • Horse(100068201) caspase 10, apoptosis-related cysteine peptidase
  • dog(488472) caspase 10, apoptosis-related cysteine peptidase

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CASP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-CASP10 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
western blot
Anti-Caspase-10 Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human
Applicazione
western blot
Anti Caspase 10 Antibody, clone 23GB3330, Rabbit Monoclonal, clone 23GB3330, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human
Applicazione
flow cytometry
immunofluorescence

western blot
Monoclonal Anti-CASP10 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
proximity ligation assay

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Caspase Inhibitor, ,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human CASP10,
Specie
human