DHFR
dihydrofolate reductase
Sinonimi:
DHFRP1, DYR
Specie:
Human DHFR (1719), Mouse Dhfr (13361), Rat Dhfr (24312), fruit fly Dhfr (42003), Zebrafish dhfr (81882), domestic guinea pig Dhfr (100729225), naked mole-rat Dhfr (101701790), domestic cat DHFR (101087964), cow DHFR (508809), dog DHFR (609048) ...Più
ID UniProtKB:
ID gene:
- Human(1719) Summary: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. [provided by RefSeq, Jul 2008]
- Mouse(13361) dihydrofolate reductase
- Rat(24312) dihydrofolate reductase
- fruit fly(42003) Dihydrofolate reductase
- Zebrafish(81882) dihydrofolate reductase
- domestic guinea pig(100729225) dihydrofolate reductase
- naked mole-rat(101701790) dihydrofolate reductase
- domestic cat(101087964) dihydrofolate reductase
- cow(508809) dihydrofolate reductase
- dog(609048) dihydrofolate reductase
- chicken(427317) dihydrofolate reductase
- Domestic Rabbit(100359209) dihydrofolate reductase
- sheep(101121421) dihydrofolate reductase
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Activity Assay
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Specie
Antibodies
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Reattività con
Applicazione
Monoclonal Anti-DHFR antibody produced in mouse, clone 2B10, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-DHFR Antibody, clone 7N3X4, Rabbit Monoclonal, ,
Reattività con
human, rat
Applicazione
western blot
Anti-DHFR, C-terminal antibody produced in rabbit, 1.0-1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
immunoprecipitation (IP)
western blot
western blot
Anti-DHFR, N-terminal antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
immunoprecipitation (IP)
western blot
western blot
Small Molecule - Inhibitor
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Kits
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Proteins
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Specie
Dihydrofolate Reductase human, ≥80% (SDS-PAGE), recombinant, expressed in E. coli, ≥1 units/mg protein,
Specie
human
esiRNA
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