LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Sinonimi:
SCDO3
Specie:
Human LFNG (3955), Mouse Lfng (16848), Rat Lfng (170905), naked mole-rat Lfng (101699763), domestic guinea pig Lfng (100730084), Zebrafish lfng (30158), chicken LFNG (395790), dog LFNG (489891), cow LFNG (516209), sheep LFNG (101112372)
ID UniProtKB:
ID gene:
- Human(3955) Summary: This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- Mouse(16848) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- Rat(170905) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- naked mole-rat(101699763) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- domestic guinea pig(100730084) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- Zebrafish(30158) lunatic fringe homolog
- chicken(395790) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- dog(489891) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- cow(516209) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
- sheep(101112372) LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-LFNG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
western blot
Monoclonal Anti-LFNG antibody produced in mouse, clone 2D10-3C11, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti LFNG Antibody, clone 23GB6595, Rabbit Monoclonal, clone 23GB6595, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human
Applicazione
flow cytometry
western blot
western blot
esiRNA
Numero di prodotto
Descrizione
Specie