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Merck

MAP2K5

mitogen-activated protein kinase kinase 5

Sinonimi:
HsT17454, MAPKK5, MEK5, PRKMK5
Specie:
ID UniProtKB:
ID gene:
  • Human(5607) Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]
  • Mouse(23938) mitogen-activated protein kinase kinase 5
  • Rat(29568) mitogen activated protein kinase kinase 5
  • Domestic Rabbit(100358715) mitogen-activated protein kinase kinase 5
  • domestic cat(101100725) mitogen-activated protein kinase kinase 5
  • sheep(101104069) mitogen-activated protein kinase kinase 5
  • chicken(415557) mitogen-activated protein kinase kinase 5
  • dog(609559) mitogen-activated protein kinase kinase 5
  • cow(100295732) mitogen-activated protein kinase kinase 5
  • domestic guinea pig(100732076) mitogen-activated protein kinase kinase 5
  • naked mole-rat(101711080) mitogen-activated protein kinase kinase 5
  • Horse(100052849) mitogen-activated protein kinase kinase 5
  • Zebrafish(100007679) mitogen-activated protein kinase kinase 5

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-MAP2K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab1,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-MAP2K5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-MAP2K5, (N-terminal) antibody produced in mouse, clone 3E10, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

western blot
Anti-MEK5 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
western blot
Monoclonal Anti-MAP2K5 antibody produced in mouse, clone 1E5, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

proximity ligation assay

western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
PD 98,059, solid,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human MAP2K5,
Specie
human
MISSION® esiRNA, targeting mouse Map2k5,
Specie
mouse