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Merck

MAPK3

mitogen-activated protein kinase 3

Sinonimi:
ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK
Specie:
ID UniProtKB:
ID gene:
  • Human(5595) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(26417) mitogen-activated protein kinase 3
  • Rat(50689) mitogen activated protein kinase 3
  • Zebrafish(399480) mitogen-activated protein kinase 3
  • domestic cat(101087958) mitogen-activated protein kinase 3
  • cow(531391) mitogen-activated protein kinase 3
  • Horse(100066173) mitogen-activated protein kinase 3
  • dog(479790) mitogen-activated protein kinase 3
  • sheep(101123008) mitogen-activated protein kinase 3
  • naked mole-rat(101702687) mitogen-activated protein kinase 3
  • domestic guinea pig(100725692) mitogen-activated protein kinase 3

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Phospho-Erk1 (pThr202 / pTyr204 + Erk2 (pTyr185/187) and pan-Erk1 / 2 ELISA Kit, for detection of phospho-erk1 and phospho-erk2 and pan-erk1/2 in human, mouse or rat cell and tissue lysates,
Specie
human
Phospho-Erk1 (pThr202 / pTyr204) + Erk2(pTyr185/187) ELISA Kit, for detection of phospho-erk1 and phospho-erk2 in human, mouse or rat cell and tissue lysates,
Specie
human
Phosphotyrosine MAPK1 / MAPK3 ELISA Kit, ,
Specie
human
Cell-Based ELISA for detecting phospho-ERK1 / 2 (pThr202 / pTyr204) in cultured cell lines, 96 assays,
Specie
mouse, rat, human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
Specie
rat, human, mouse

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
KD-Validated Anti ERK1 Antibody, clone 23GB2455, Rabbit Monoclonal, clone 23GB2455, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
western blot
KD-Validated Anti ERK1 Antibody, clone 23GB2450, Rabbit Monoclonal, clone 23GB2450, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human
Applicazione
flow cytometry
immunofluorescence

western blot
Anti-phospho-Erk1 (Thr202/Tyr204) + Erk2 (Thr185/Tyr187) Antibody, clone 23GB4520, Rabbit Monoclonal, clone 23GB4520, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human
Applicazione
flow cytometry
immunofluorescence

western blot
Anti-phospho-ERK1/2 (pThr202/Tyr204) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot
Milli-Mark Anti-Phospho-Erk1/2 Antibody (Thr202/Tyr204, Thr185/Tyr187)-PE, clone AW39R, Milli-Mark®, from rabbit,
Reattività con
human, mouse, rat
Applicazione
flow cytometry
western blot

Proteins

Numero di prodotto
Descrizione
Specie
ERK1, active, untagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
MAP Kinase 1/Erk1 Protein, active, 10 µg, Active, recombinant, full-length, human MAP Kinase 1/Erk1 containing an N-terminal GST tag, for use in Kinase Assays.,
Specie
human
ERK1, active, GST tagged human, PRECISIO®, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Mapk3,
Specie
mouse
MISSION® esiRNA, targeting human MAPK3,
Specie
human