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Merck

MCM2

minichromosome maintenance complex component 2

Sinonimi:
BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19
Specie:
ID UniProtKB:
ID gene:
  • Human(4171) Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
  • Mouse(17216) minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
  • Rat(312538) minichromosome maintenance complex component 2
  • fruit fly(40973) Minichromosome maintenance 2
  • Thale Cress(841056) minichromosome maintenance protein 2
  • domestic guinea pig(100722936) minichromosome maintenance complex component 2
  • naked mole-rat(101710978) minichromosome maintenance complex component 2
  • sheep(101116097) minichromosome maintenance complex component 2
  • cow(510120) minichromosome maintenance complex component 2
  • domestic cat(101090176) minichromosome maintenance complex component 2
  • dog(484622) minichromosome maintenance complex component 2
  • chicken(416027) minichromosome maintenance complex component 2
  • Zebrafish(192338) MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-MCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-MCM2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Rabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified, ,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot
Anti-MCM2 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP85, affinity isolated antibody,
Reattività con
bovine, dog, frog, human, mouse, rat
Applicazione
flow cytometry
immunohistochemistry

western blot
Anti-MCM2 Antibody, clone 0Q10S9, Rabbit Monoclonal, ,
Reattività con
human, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human MCM2,
Specie
human
MISSION® esiRNA, targeting mouse Mcm2,
Specie
mouse