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Merck

MUC1

mucin 1, cell surface associated

Sinonimi:
CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM
Specie:
ID UniProtKB:
ID gene:
  • Human(4582) Summary: This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
  • Mouse(17829) mucin 1, transmembrane
  • Rat(24571) mucin 1, cell surface associated
  • dog(448784) mucin 1, cell surface associated
  • naked mole-rat(101702421) mucin 1, cell surface associated
  • domestic cat(101093832) mucin 1, cell surface associated
  • chicken(426412) mucin 1, cell surface associated
  • domestic cat(100294522) mucin 1, cell surface associated
  • cow(281333) mucin 1, cell surface associated
  • domestic guinea pig(100733534) mucin 1, cell surface associated
  • sheep(100294589) mucin 1, cell surface associated
  • sheep(101106133) mucin 1, cell surface associated
  • Domestic Rabbit(100009240) mucin 1, cell surface associated

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human Carbohydrate Antigen 15-3 / Mucin-1 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
EMA (E29) Mouse Monoclonal Antibody, ,
Reattività con
human
Applicazione
immunohistochemistry
Anti-MUC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
MUC1 (MRQ-17) Mouse Monoclonal Antibody, ,
Reattività con
human
Applicazione
immunohistochemistry
Anti-MUC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-MUC1 Antibody, clone HMFG2, clone HMFG2, from mouse,
Reattività con
human
Applicazione
immunohistochemistry
immunoprecipitation (IP)

western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human MUC1,
Specie
human