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Merck

NF2

neurofibromin 2 (merlin)

Sinonimi:
ACN, BANF, SCH
Specie:
ID UniProtKB:
ID gene:
  • Human(4771) Summary: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. [provided by RefSeq, Jul 2008]
  • Mouse(18016) neurofibromatosis 2
  • Rat(25744) neurofibromin 2 (merlin)
  • chicken(395158) neurofibromin 2 (bilateral acoustic neuroma)
  • domestic cat(101087787) neurofibromin 2 (merlin)
  • dog(477535) neurofibromin 2 (merlin)
  • cow(540479) neurofibromin 2 (merlin)
  • Horse(100058977) neurofibromin 2 (merlin)
  • Domestic Rabbit(100357691) neurofibromin 2 (merlin)
  • sheep(101107995) neurofibromin 2 (merlin)
  • naked mole-rat(101706100) neurofibromin 2 (merlin)
  • domestic guinea pig(100715365) neurofibromin 2 (merlin)

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-NF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-NF2 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
KD-Validated Anti NF2 / Merlin Antibody, clone 23GB2620, Rabbit Monoclonal, clone 23GB2620, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
immunofluorescence

western blot
Anti-Merlin Antibody, clone 1H15-L1 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey, mouse, rat
Applicazione
affinity binding assay
immunoprecipitation (IP)

western blot
Anti- NF2 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human NF2,
Specie
human