Passa al contenuto
Merck

PIM1

pim-1 oncogene

Sinonimi:
PIM
Specie:
ID UniProtKB:
ID gene:
  • Human(5292) Summary: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
  • Mouse(18712) proviral integration site 1
  • Rat(24649) pim-1 oncogene
  • chicken(100858838) pim-1 oncogene
  • sheep(100272002) pim-1 oncogene
  • Horse(100053898) pim-1 oncogene
  • Zebrafish(58054) pim-1 oncogene
  • cow(281402) pim-1 oncogene
  • naked mole-rat(101706236) pim-1 oncogene
  • dog(481772) pim-1 oncogene
  • domestic guinea pig(100724588) pim-1 oncogene
  • domestic cat(493888) pim-1 oncogene

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
ANTI-PIM1 antibody produced in mouse, clone 3D12, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

western blot
ANTI-PIM1 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-Pim-1 (pTyr309) antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
western blot
Monoclonal Anti-PIM1 antibody produced in mouse, clone 6A2, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry
ANTI-PIM1 antibody produced in mouse, clone 1C12, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot

Proteins

Numero di prodotto
Descrizione
Specie
PIM1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human PIM1,
Specie
human
MISSION® esiRNA, targeting mouse Pim1,
Specie
mouse