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Merck

SLC6A3

solute carrier family 6 (neurotransmitter transporter), member 3

Sinonimi:
DAT, DAT1, PKDYS
Specie:
ID UniProtKB:
ID gene:
  • Human(6531) Summary: This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009]
  • Mouse(13162) solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  • Rat(24898) solute carrier family 6 (neurotransmitter transporter), member 3
  • domestic guinea pig(100714898) solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  • naked mole-rat(101709245) solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  • sheep(101111908) solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  • dog(609304) solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  • domestic cat(101101618) solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  • Horse(100054747) solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  • cow(788410) solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
  • Zebrafish(80787) solute carrier family 6 (neurotransmitter transporter, dopamine), member 3

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
N-etilmaleimide, purum p.a., ≥99.0% (HPLC),
Specie
human
N-etilmaleimide, BioUltra, ≥99.0% (HPLC),
Specie
human
N-etilmaleimide, BioXtra, ≥98% (HPLC),
Specie
human
Modafinil, ≥98% (HPLC),
Specie
rat, human
4-Benzylpyridine, 98%,
Specie
rat

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anticorpo anti-trasportatore della dopamina, NT, clone DAT-Nt, culture supernatant, clone DAT-Nt, Chemicon®,
Reattività con
human, monkey, mouse, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Anti-Dopamine Transporter Antibody, Chemicon®, from rabbit,
Reattività con
mouse, rat
Applicazione
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anticorpo anti-trasportatore della dopamina, loop extracellulare 2, Chemicon®, from rabbit,
Reattività con
human, monkey
Applicazione
immunohistochemistry
western blot
Anti-Dopamine Transporter, Extracellular Loop 2 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, monkey
Applicazione
immunohistochemistry
western blot
Anti-SLC6A3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Modafinil solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Modafinil, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Modafinil for system suitability, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Methylphenidate hydrochloride, ,
Specie
human
Methylphenidate hydrochloride solution, ampule of 1 mL, (Racemic mixture), 1.0 mg/mL in methanol (as free base), certified reference material, Cerilliant®,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human SLC6A3,
Specie
human