Passa al contenuto
Merck

SRC

v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

Sinonimi:
ASV, SRC1, c-SRC, p60-Src
Specie:
Human SRC (6714), Mouse Src (20779), Rat Src (83805), Zebrafish src (325084), chicken SRC (396442), domestic cat SRC (101100378), dog SRC (485864), sheep SRC (101103084), cow SRC (535742), domestic guinea pig Src (100728509)
ID UniProtKB:
P12931, E1P5V4, Q76P87, Q86VB9, Q9H5A8
ID gene:
  • Human(6714) Summary: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20779) Rous sarcoma oncogene
  • Rat(83805) v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
  • Zebrafish(325084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • chicken(396442) v-src sarcoma viral oncogene
  • domestic cat(101100378) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • dog(485864) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • sheep(101103084) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • cow(535742) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
  • domestic guinea pig(100728509) Rous sarcoma oncogene
  • naked mole-rat(101703827) v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
695017
Acido fosforico, ACS reagent, ≥85 wt. % in H2O,
Specie
human
438081
Acido fosforico, ACS reagent, ≥85 wt. % in H2O,
Specie
human
27109
Acido citrico, meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance),
Specie
human
345245
Acido fosforico, 85 wt. % in H2O, 99.99% trace metals basis,
Specie
human
251275
Acido citrico, ACS reagent, ≥99.5%,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
SAB6012515
KD-Validated Anti-phospho-Src (Tyr419) Antibody, clone 23GB4080, Rabbit Monoclonal, clone 23GB4080, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
western blot
SAB6012526
KD-Validated Anti-phospho-Src (Tyr529) Antibody, clone 23GB6690, Rabbit Monoclonal, clone 23GB6690, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
western blot
SAB6012539
KD-Validated Anti Src Antibody, clone 23GB1110, Rabbit Monoclonal, clone 23GB1110, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
immunofluorescence
western blot
SAB6012540
KD-Validated Anti Src Antibody, clone 23GB985, Rabbit Monoclonal, clone 23GB985, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
immunofluorescence
western blot
SAB6012542
KD-Validated Anti Src Antibody, clone 23GB980, Rabbit Monoclonal, clone 23GB980, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
immunofluorescence
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
S9692
SU 6656, ≥98% (HPLC),
Specie
human
R2146
Radicicol from Diheterospora chlamydosporia, solid,
Specie
human, rat
E2250
Ellagic acid, ≥95% (HPLC), powder, from tree bark,
Specie
human, rat
T182
Tyrphostin A9, solid,
Specie
mouse, human
SML2589
Dasatinib, ≥98% (HPLC),
Specie
human

Kits

Numero di prodotto
Descrizione
Specie
20-121
Src Kinase Reaction Buffer, ,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
S1076
SRC, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human
14-326-M
Src Protein, active, 10 µg, Active, N-Terminal His6-tagged, recombinant, full-length, human Src. For use in Kinase Assays.,
Specie
human
14-746-M
Src (1-530) Protein, active, 10 µg, ,
Specie
human
14-748-M
Src (T341M) Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, full-length human Src, containing the T341M mutation. For use in Kinase Assays.,
Specie
human
S5564
SRC N1 human, ≥60% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EMU071351
MISSION® esiRNA, targeting mouse Src,
Specie
mouse

Small Molecule - Substrate

Numero di prodotto
Descrizione
Specie
12-140
Src Substrate Peptide, Src Substrate Peptide primarily used in Kinase Assays.,
Specie
human