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Merck

USP5

ubiquitin specific peptidase 5 (isopeptidase T)

Sinonimi:
ISOT
Specie:
ID UniProtKB:
ID gene:
  • Human(8078) Summary: Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]
  • Mouse(22225) ubiquitin specific peptidase 5 (isopeptidase T)
  • Rat(297593) ubiquitin specific peptidase 5 (isopeptidase T)
  • chicken(418290) ubiquitin specific peptidase 5 (isopeptidase T)
  • domestic cat(101085296) ubiquitin specific peptidase 5 (isopeptidase T)
  • cow(505280) ubiquitin specific peptidase 5 (isopeptidase T)
  • naked mole-rat(101720419) ubiquitin specific peptidase 5 (isopeptidase T)
  • dog(486718) ubiquitin specific peptidase 5 (isopeptidase T)
  • sheep(101109954) ubiquitin specific peptidase 5 (isopeptidase T)
  • Zebrafish(406618) ubiquitin specific protease 5
  • Horse(100060068) ubiquitin specific peptidase 5 (isopeptidase T)
  • domestic guinea pig(100724997) ubiquitin specific peptidase 5 (isopeptidase T)

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Monoclonal Anti-USP5 antibody produced in mouse, clone 4G4, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
Anti-USP5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
immunohistochemistry

western blot
KD-Validated Anti Ubiquitin Specific Peptidase 5 Antibody, clone 24GB2480, Rabbit Monoclonal, clone 24GB2480, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
immunofluorescence

western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human USP5,
Specie
human
MISSION® esiRNA, targeting mouse Usp5,
Specie
mouse