Merck

The fast-changing landscape of cannabis and hemp legalization for medicinal and adult recreational purposes presents unique testing challenges from identification of cultivars to potency and safety. Standardized reliable and robust sample preparation protocols and analytical methods are required to analyze cannabinoids, terpene content, residual pesticides and mycotoxins, residual solvents, moisture, heavy metals and microbial contaminants in cannabis and hemp products. Products range from flower buds and plant extracts to oils and cannabis-infused or CBD-containing foods, beverages and cosmetics. Analytical techniques such as HPLC-UV, LC-MS or LC-MS/MS, GC-FID, GC-MS or GC-MS/MS aid in the fast, sensitive and accurate means of quantification of analytes. The careful choice of high-quality standards, solvents, and chromatography consumables is also paramount to detecting traces of interfering contaminants for comprehensive cannabis profiling.

Cannabinoids analysis in cannabis and hemp using HPLC and GC techniques
Cannabinoid Profiling and Potency Testing of Cannabis and Cannabis Products

Analytical testing workflows for determination of cannabinoids in cannabis and hemp products by HPLC coupled to UV or MS and/or GC paired with FID/MS to address potency and quality requirements. 

Profiling terpenes in cannabis to determine the purity, quality and identity of cannabis strains by using GC-MS while meeting legal and regulatory requirements.
Terpenes in Cannabis: Profile and Importance

Comprehensive analytical workflow for identification and quantitation of cannabis terpenes by GC-MS to support strain identification and flavor profiling applications.

Residual pesticide and mycotoxin analysis in Cannabis & hemp using LC-MS/MS and GC-MS/MS to meet regulatory requirements.
Pesticides and Mycotoxins in Cannabis and Hemp

Complete LC-MS/MS and GC-MS/MS methods for analysis of pesticides and mycotoxins in cannabis and hemp to support regulatory compliance and consumer safety.