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Request a Sample for Cell Lysis or DNA Digestion

Benzonase® Salt Tolerant Endonuclease

The production process of adeno-associated virus (AAV) vectors involves a midstream step that combines cell lysis and nuclease treatment.

Detergents, such as zwitterionic non-ionic surfactants, are used in biomanufacturing processes for a variety of applications including viral inactivation and cell lysis. Our Deviron® portfolio of sustainable detergents should be considered as a primary alternative to TRITON™ X-100 by all biologics manufacturers.

In viral vector purification, free nucleic acid not only poses a threat to patient safety but also decreases product yield. Our Benzonase® portfolio helps remove this unwanted DNA and RNA from your process, even in high salt concentrations with our NEW GMP grade Benzonase® Salt Tolerant endonuclease.

To request a sample of either Benzonase® or Deviron® portfolio products, please complete the webform below and a technical expert will be in touch with you soon.

To refer back to our technical article page, please click here.

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