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239488

Sigma-Aldrich

1,4-Bis(3-aminopropyl)piperazine

≥99%

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Synonym(s):
1,4-(3-Aminopropyl)piperazine, 1,4-Piperazinebis(propylamine), 1,4-Piperazinedipropylamine, N,N′-Bis(γ-aminopropyl)piperazine, N,N′-Bis(3-aminopropyl)piperazine, [3-[4-(3-Aminopropyl)piperazin-1-yl]propyl]amine
Empirical Formula (Hill Notation):
C10H24N4
CAS Number:
Molecular Weight:
200.32
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

vapor density

6.9 (vs air)

Assay

≥99%

form

liquid

refractive index

n20/D 1.502 (lit.)

bp

150-152 °C/2 mmHg (lit.)

mp

15 °C (lit.)

density

0.973 g/mL at 25 °C (lit.)

SMILES string

NCCCN1CCN(CCCN)CC1

InChI

1S/C10H24N4/c11-3-1-5-13-7-9-14(10-8-13)6-2-4-12/h1-12H2

InChI key

XUSNPFGLKGCWGN-UHFFFAOYSA-N

Gene Information

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This Item
290203473316B45402
vibrant-m

239488

1,4-Bis(3-aminopropyl)piperazine

vibrant-m

290203

3,5-Difluorobenzonitrile

vibrant-m

473316

Amylamines, mixture of isomers

vibrant-m

B45402

1,4-Bis(2-hydroxyethyl)piperazine

assay

≥99%

assay

99%

assay

≥98%

assay

99%

refractive index

n20/D 1.502 (lit.)

refractive index

-

refractive index

n20/D 1.411 (lit.)

refractive index

-

form

liquid

form

solid

form

-

form

crystals

mp

15 °C (lit.)

mp

84-86 °C (lit.)

mp

−55 °C (lit.)

mp

133.5-136 °C (lit.)

density

0.973 g/mL at 25 °C (lit.)

density

-

density

0.752 g/mL at 25 °C (lit.)

density

-

General description

The thermodynamic parameters for protonation of 1,4-bis(3-aminopropyl)-piperazine (BAPP) were studied in aqueous solution using a potentiometric technique.

Application

1,4-Bis(3-aminopropyl)piperazine was used to functionalize natural montmorillonite (M) and synthetic kanemite (K).

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

325.4 °F - closed cup

Flash Point(C)

163 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

FSL

Flammable liquids
Type 3 petroleums
Hazardous rank III
Water insoluble liquid


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Thermodynamic parameters for protonation of 1,4-bis(3-aminopropyl)-piperazine (BAPP) and its metal complexation with some divalent metal ions were determined in aqueous solution at constant ionic strength (0.1 M NaNO(3)) using a potentiometric technique. The order of -ΔG(0) and -ΔH(0) was found to
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Molecular pharmaceutics, 11(7), 2250-2261 (2014-06-04)
A folate-decorated, disulfide-based cationic dextran conjugate having dextran as the main chain and disulfide-linked 1,4-bis(3-aminopropyl)piperazine (BAP) residues as the grafts was designed and successfully prepared as a multifunctional gene delivery vector for targeted gene delivery to ovarian cancer SKOV-3 cells

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