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Merck

900741

Gelatin methacryloyl

gel strength 170-195 g Bloom, degree of substitution: 60%

Synonym(s):

GelMA, Gelatin methacrylamide, Gelatin methacrylate, GelMa, Gelatin Methacrylate

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¥37,200

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About This Item

Linear Formula:
(C40H59N11O13)n
UNSPSC Code:
12162002
NACRES:
NA.23

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Quality Level

form

solid

storage temp.

2-8°C

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This Item
900628900622900496
form

solid

form

solid

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

Application

Gelatin methacrylate can be used to form cross-linked hydrogels for tissue engineering[1] and 3D printing.[2][3][4] It has been used for endothelial cell morphogenesis,[5] cardiomyocytes,[6] epidermal tissue,[7] injectable tissue constructs,[8] bone differentiation,[9] and cartilage regeneration.[10] Gelatin methacrylate has been explored in drug delivery applications in the form of microspheres[11] and hydrogels.[12]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

900741-1G:
900741-VAR:
900741-BULK:


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Facile one-step micropatterning using photodegradable methacrylated gelatin hydrogels for improved cardiomyocyte organization and alignment.
Tsang K, et al.
Advances in Functional Materials, 25(6), 977-986 (2015)
Photocrosslinkable gelatin hydrogel for epidermal tissue engineering.
Zhao X, et al.
Advanced Helathcare Materials (2015)
Covalent attachment of a three-dimensionally printed thermoplast to a gelatin hydrogel for mechanically enhanced cartilage constructs.
Boere KWM, et al.
Acta Biomaterialia, 10(6), 2602-2611 (2014)
Anh H Nguyen et al.
Acta biomaterialia, 13, 101-110 (2014-12-03)
Gelatin has been commonly used as a delivery vehicle for various biomolecules for tissue engineering and regenerative medicine applications due to its simple fabrication methods, inherent electrostatic binding properties, and proteolytic degradability. Compared to traditional chemical cross-linking methods, such as
Heemin Kang et al.
Acta biomaterialia, 10(12), 4961-4970 (2014-08-26)
Human induced pluripotent stem cells (hiPSC) are a promising cell source with pluripotency and self-renewal properties. Design of simple and robust biomaterials with an innate ability to induce lineage-specificity of hiPSC is desirable to realize their application in regenerative medicine.

Articles

Shrike Zhang教授(Harvard Medical School、米国)が、in vitroの薬物試験のための3Dバイオプリンティング組織モデルの進展について述べ、バイオインクの選択基準と組織モデルのバイオファブリケーションにおける3Dバイオプリンティングの応用例を紹介します。

高分解能の3Dプリンティングを含むバイオファブリケーションに向けたゼラチン-メタクリルアミド(GelMA)などの光架橋性誘導体などを紹介します。

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.

Protocols

Frequently asked questions (FAQs) for KAPA SYBR® FAST One-Step qRT-PCR Kits.

Related Content

Tissue engineering fabricates tissues cultures from scaffolds, living cells, and biologically active molecules by simulating the microenvironment of the body to repair or replace damaged tissue.

ゼラチンメタクリロイルは、複合ヒドロゲルプラットフォームを作製するために広く使用されている材料です。

組織工学では、損傷した組織を修復または置き換えるために、体内の微小環境を模倣して、足場、生きた細胞、生物学的活性分子から組織を構築します。

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