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Merck

916471

PhotoHA™ -LAP, methacrylated hyaluronic acid bioink kit, with LAP

Synonym(s):

3D Bioprinting, Bioink, HAMA, Hyaluronic acid

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About This Item

NACRES:
NA.23
UNSPSC Code:
12352201

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description

Methacrylated collagen:
Degree of methacrylation: ≥45-65%

sterility

sterile; sterile-filtered

storage temp.

−20°C

Quality Level

100

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PhotoHA™ -LAP, methacrylated hyaluronic acid bioink kit, with LAP

Sigma-Aldrich

916471

PhotoHA™ -LAP, methacrylated hyaluronic acid bioink kit, with LAP

PhotoHA™-IRG, methacrylated hyaluronic acid bioink kit, with Irgacure

Sigma-Aldrich

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PhotoHA™-IRG, methacrylated hyaluronic acid bioink kit, with Irgacure

PhotoHA™-RUT methacrylated hyaluronic acid bioink kit, with ruthenium

Sigma-Aldrich

917338

PhotoHA™-RUT

Sigma-Aldrich

Sigma-Aldrich

916293

PhotoCol™-LAP

sterility

sterile; sterile-filtered

sterility

sterile; sterile-filtered

sterility

sterile; sterile-filtered

sterility

sterile; sterile-filtered

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

description

Methacrylated collagen:
Degree of methacrylation: ≥45-65%

description

Methacrylated hyaluronic acid:
Degree of methacrylation: ≥ 45-65%

description

Methacrylated hyaluronic acid:
Degree of methacrylation: ≥ 45-65%, Product components :
Methacrylated hyaluronic acid (100 mg)
Ruthenium (100 mg)
Sodium persulfate photoinitiator (500 mg)

description

Methacrylated collagen:
Degree of methacrylation ≥ 20%, Product components :

  • Methacrylated collagen (100 mg)
  • 20 mM acetic acid (50 mL)
  • Neutralization solution (10 mL)
  • LAP photoinitiator (100 mg)

Application

PhotoHA™ -LAP bioink kit consists of methacrylated hyaluronic acid (HAMA) and LAP photoinitiator. Hyaluronic acid is the most abundant glycosaminoglycan in the body being an important component of several tissues throughout the body. While it is abundant in extracellular matrices, hyaluronic acid also contributes to tissue hydrodynamics, movement and proliferation of cells, and participates in a number of cell surface receptor interactions. The photoinitiator consists of LAP to be formulated in 1X cell culture media or PBS, which allows blue light photocrosslinking of the printed structure at 405 nm. PhotoHA™ -LAP provides native-like 3D HA gels, and the final gel stiffness can be customized by changing HA concentrations and crosslinking.

Legal Information

PhotoHA is a trademark of Advanced BioMatrix, Inc.

Storage Class

11 - Combustible Solids

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ7937
MKCV9827
MKCW3194
MKCR6536

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Michelle T Poldervaart et al.
PloS one, 12(6), e0177628-e0177628 (2017-06-07)
In bone regenerative medicine there is a need for suitable bone substitutes. Hydrogels have excellent biocompatible and biodegradable characteristics, but their visco-elastic properties limit their applicability, especially with respect to 3D bioprinting. In this study, we modified the naturally occurring
Sudhir Khetan et al.
Cryobiology, 90, 83-88 (2019-08-06)
While significant progress has been made in directing the behavior of cells encapsulated within three-dimensional (3D) covalently crosslinked hydrogels, the capacity of these materials to support in situ cryopreservation of cells directly within the gels has not been assessed. Here

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