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Merck

917575

PhotoCol™-IRG, methacrylated collagen bioink kit, with Irgacure

Synonym(s):

3D Bioprinting, Bioink, Collagen

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About This Item

NACRES:
NA.23
UNSPSC Code:
12352201

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description

Methacrylated collagen:
Degree of methacrylation ≥ 20%
Product components :
Methacrylated collagen (100 mg)
20 mM acetic acid (50 mL)
Neutralization solution (10 mL)
Irgacure photoinitiator ( 100 mg)

sterility

sterile; sterile-filtered

impurities

≤10 EU/mL Endotoxin

storage temp.

2-8°C

Quality Level

100

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PhotoCol™-IRG, methacrylated collagen bioink kit, with Irgacure

Sigma-Aldrich

917575

PhotoCol™-IRG, methacrylated collagen bioink kit, with Irgacure

PhotoCol™-RUT, methacrylated collagen bioink kit, with ruthenium

Sigma-Aldrich

917834

PhotoCol™-RUT, methacrylated collagen bioink kit, with ruthenium

Sigma-Aldrich

Sigma-Aldrich

916293

PhotoCol™-LAP

PhotoHA™-IRG, methacrylated hyaluronic acid bioink kit, with Irgacure

Sigma-Aldrich

917079

PhotoHA™-IRG, methacrylated hyaluronic acid bioink kit, with Irgacure

sterility

sterile; sterile-filtered

sterility

sterile; sterile-filtered

sterility

sterile; sterile-filtered

sterility

sterile; sterile-filtered

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

description

Methacrylated collagen:
Degree of methacrylation ≥ 20%

description

Methacrylated collagen:
Degree of methacrylation ≥ 20%, Product components :
Methacrylated collagen (100 mg)
20 mM acetic acid (50 mL)
Neutralization solution (10 mL)
, Ruthenium (100 mg)
Sodium persulfate photoinitiator (500 mg)

description

Methacrylated collagen:
Degree of methacrylation ≥ 20%, Product components :

  • Methacrylated collagen (100 mg)
  • 20 mM acetic acid (50 mL)
  • Neutralization solution (10 mL)
  • LAP photoinitiator (100 mg)

description

Methacrylated hyaluronic acid:
Degree of methacrylation: ≥ 45-65%

impurities

≤10 EU/mL Endotoxin

impurities

≤10 EU/mL Endotoxin

impurities

≤10 EU/mL Endotoxin

impurities

-

Application

PhotoCol™-IRG bioink kit consists of purified methacrylated Type I bovine collagen as the core component with other support reagents. The methacrylated Type I collagen is produced from telo-peptide intact bovine collagen where the collagen has been modified by reacting the free amines, primarily the ε-amines groups of the lysine residues as well as the a-amines groups on the N-termini. Over 20% of the total lysine residues of the collagen molecule have been methacrylated. A bottle of 20 mM acetic acid solution is provided to solubilize the lyophilized methacrylated collagen at concentrations ranging from 3 to 8 mg/ml. The neutralization solution consists of an alkaline 10X phosphate buffered saline (PBS) solution which provides physiological salts and pH in the final mixture. The photoinitiator consists of Irgacure 2959 to be formulated in methanol (methanol not included), which allows UV crosslinking of the printed structure at 365 nm. PhotoCol™-IRG provides native-like 3D collagen gels, and the final gel stiffness can be customized by changing collagen concentrations and crosslinking.

Legal Information

PhotoCol is a trademark of Advanced BioMatrix, Inc.

pictograms

Environment
GHS09

hcodes

H411

Hazard Classifications

Aquatic Chronic 2

Storage Class

10 - Combustible liquids

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ7936
MKCX8237
MKCV9830
MKCW4781
MKCT0358

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Tissue engineering. Part C, Methods, 24(2), 74-88 (2017-10-21)
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With the increase in knowledge on the importance of the tumor microenvironment, cell culture models of cancers can be adapted to better recapitulate physiologically relevant situations. Three main microenvironmental factors influence tumor phenotype: the biochemical components that stimulate cells, the
Andrea Mazzocchi et al.
Biofabrication, 11(1), 015003-015003 (2018-10-03)
Current 3D printing of tissue is restricted by the use of biomaterials that do not recapitulate the native properties of the extracellular matrix (ECM). These restrictions have thus far prevented optimization of composition and structure of the in vivo tissue
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