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850365C

Avanti

18:0 PC (DSPC)

Avanti Polar Lipids

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Synonym(s):
1,2-dioctadecanoyl-sn-glycero-3-phosphocholine; DSPC; PC(18:0/18:0)
Empirical Formula (Hill Notation):
C44H88NO8P
CAS Number:
Molecular Weight:
790.15
NACRES:
NA.25

description

1,2-distearoyl-sn-glycero-3-phosphocholine, chloroform

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850365C-25mg)
pkg of 1 × 20 mL (850365C-500mg)
pkg of 2 × 20 mL (850365C-1g)
pkg of 2 × 4 mL (850365C-200mg)

manufacturer/tradename

Avanti Polar Lipids

concentration

10 mg/mL (850365C-25mg)
25 mg/mL (850365C-1g)
25 mg/mL (850365C-200mg)
25 mg/mL (850365C-500mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

InChI key

NRJAVPSFFCBXDT-HUESYALOSA-N

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This Item
850365P850375C850385C
18:0 PC (DSPC) Avanti Polar Lipids

850365C

18:0 PC (DSPC)

18:0 PC (DSPC) Avanti Polar Lipids

850365P

18:0 PC (DSPC)

18:1 (Δ9-Cis) PC (DOPC) Avanti Polar Lipids

850375C

18:1 (Δ9-Cis) PC (DOPC)

18:2 (Cis) PC (DLPC) 1,2-dilinoleoyl-sn-glycero-3-phosphocholine, chloroform

850385C

18:2 (Cis) PC (DLPC)

packaging

pkg of 1 × 2.5 mL (850365C-25mg), pkg of 2 × 20 mL (850365C-1g), pkg of 1 × 20 mL (850365C-500mg), pkg of 2 × 4 mL (850365C-200mg)

packaging

pkg of 1 × 1 g (850365P-1G), pkg of 1 × 200 mg (850365P-200MG), pkg of 1 × 25 mg (850365P-25MG), pkg of 1 × 500 mg (850365P-500MG)

packaging

pkg of 1 × 2.5 mL (850375C-25mg), pkg of 2 × 20 mL (850375C-1g), pkg of 2 × 4 mL (850375C-200mg), pkg of 5 × 4 mL (850375C-500mg)

packaging

pkg of 1 × 2.5 mL (850385C-25mg), pkg of 2 × 4 mL (850385C-200mg)

form

liquid

form

powder

form

liquid

form

liquid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

concentration

10 mg/mL (850365C-25mg), 25 mg/mL (850365C-200mg), 25 mg/mL (850365C-1g), 25 mg/mL (850365C-500mg)

concentration

-

concentration

10 mg/mL (850375C-25mg), 25 mg/mL (850375C-1g), 25 mg/mL (850375C-200mg), 25 mg/mL (850375C-500mg)

concentration

10 mg/mL (850385C-25mg), 25 mg/mL (850385C-200mg)

General description

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

18:0 PC (DSPC) has been used in the preparation of microbubbles (MBs). It is suitable for use in the synthesis of methylene blue (MB)-liposome synthesis and in the preparation of unilamellar vesicles

Biochem/physiol Actions

18:0 PC (DSPC) liposomes/1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine, along with Rhamnolipids (RLs) can serve as the best combination for drug delivery application. It can help to maintain the stability of curcumin.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850365C-1g)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850365C-500mg)
5 mL Clear Glass Sealed Ampule (850365C-200mg)
5 mL Clear Glass Sealed Ampule (850365C-25mg)

also commonly purchased with this product

Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(C)

does not flash


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Interaction of curcumin with 1, 2-dioctadecanoyl-sn-glycero-3-phosphocholine liposomes: Intercalation of rhamnolipids enhances membrane fluidity, permeability and stability of drug molecule
Moussa Z, et al.
Colloids and Surfaces. B, Biointerfaces, 149, 30-37 (2017)
Methylene-Blue-Encapsulated Liposomes as Photodynamic Therapy Nano Agents for Breast Cancer Cells
Wu PT, et al.
Nanomaterials, 9(1), 14-14 (2019)
Ana Reis et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183133-183133 (2019-12-01)
Food polyphenols in fruits juices, tea, coffee, wine and beer confer sensory properties such as colour, astringency and bitterness. The development of functional healthy drinks without the unpleasant sensory feeling is boosting research for a clearer understanding on the interactions
In vivo transfection and detection of gene expression of stem cells preloaded with DNA-carrying microbubbles
Tavri S, et al.
Radiology, 276(2), 518-525 (2015)
Joshua Owen et al.
Langmuir : the ACS journal of surfaces and colloids, 35(31), 10014-10024 (2018-11-30)
Phospholipid coated microbubbles are currently in widespread clinical use as ultrasound contrast agents and under investigation for therapeutic applications. Previous studies have demonstrated the importance of the coating nanostructure in determining microbubble stability and its dependence upon both composition and

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